Formulation, development and optimization of raloxifene-loaded chitosan nanoparticles for treatment of osteoporosis
D Saini, M Fazil, MM Ali, S Baboota, Ameeduzzafar… - Drug …, 2015 - Taylor & Francis
Context: Osteoporosis (OP) is a disease of skeletal system and is associated with fragility
fracture at the hip, spine and wrist. Various drugs have been used to treat OP. One of them is …
fracture at the hip, spine and wrist. Various drugs have been used to treat OP. One of them is …
Riluzole-loaded nanoparticles to alleviate the symptoms of neurological disorders by attenuating oxidative stress
Purpose: The objective of the research undertaken was to develop the Riluzole (RIZ)
nanoparticles drug delivery system using Transferrin (Tf) as a ligand in the brain. Method …
nanoparticles drug delivery system using Transferrin (Tf) as a ligand in the brain. Method …
Nanoparticle mediated brain targeted delivery of gallic acid: in vivo behavioral and biochemical studies for improved antioxidant and antidepressant-like activity
Context: Gallic acid had been reported to possess antidepressant like activity, which may be
attributed to its CNS effects like increase in reduced glutathione levels, increased catalase …
attributed to its CNS effects like increase in reduced glutathione levels, increased catalase …
Gellan gum-based hydrogel for the transdermal delivery of nebivolol: Optimization and evaluation
Poor solubility and appreciable first-pass metabolism have limited the oral bioavailability of
nebivolol. The objective of the current investigation was to design, formulate, and optimize a …
nebivolol. The objective of the current investigation was to design, formulate, and optimize a …
Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials
D Huang, W Liao, J Li, T Chen, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …
constitutes the third most common cause of death among elderly individuals. AD patients …
Eudragit®-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers
Aim Etoricoxib is a selective inhibitor of COX-2 enzyme. It is proposed as a potent anti-
inflammatory drug intended for the control of irritable bowel syndrome. The current work …
inflammatory drug intended for the control of irritable bowel syndrome. The current work …
Mesoporous silica nanoparticles for efficient rivastigmine hydrogen tartrate delivery into SY5Y cells
M Karimzadeh, L Rashidi, F Ganji - Drug development and …, 2017 - Taylor & Francis
Rivastigmine hydrogen tartrate (RT) is a molecule with both hydrophilic and hydrophobic
properties used for the treatment of the Alzheimer's disease. In this work, the larger pore size …
properties used for the treatment of the Alzheimer's disease. In this work, the larger pore size …
Advances in nanomedicine for the treatment of Alzheimer's and Parkinson's diseases
S Hernando, O Gartziandia, E Herran, JL Pedraz… - …, 2016 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are the most common neurodegenerative
diseases worldwide. Despite all the efforts made by the scientific community, current …
diseases worldwide. Despite all the efforts made by the scientific community, current …
Formulation of polymeric nanoparticles of antidepressant drug for intranasal delivery
Aim: The manuscript describes the performance of nanoparticles loaded with antidepressant
drug for nose-to-brain drug delivery. Materials & methods: Poly-lactic-co-glycolic acid …
drug for nose-to-brain drug delivery. Materials & methods: Poly-lactic-co-glycolic acid …
Bioinspired lipid-polysaccharide modified hybrid nanoparticles as a brain-targeted highly loaded carrier for a hydrophilic drug
Lipid-polysaccharide modified biohybrid nanoparticles (NPs) are eminent drug carriers for
brain targeting, owing to their ability to prolong the circulation time and penetrate the blood …
brain targeting, owing to their ability to prolong the circulation time and penetrate the blood …