Implantable hemodynamic monitors improve survival in patients with heart failure and reduced ejection fraction

JA Lindenfeld, MR Costanzo, MR Zile… - Journal of the American …, 2024 - jacc.org
Background Trials evaluating implantable hemodynamic monitors to manage patients with
heart failure (HF) have shown reductions in HF hospitalizations but not mortality. Prior meta …

New trends in pulmonary hypertension

S Cullivan, S Gaine, O Sitbon - European Respiratory Review, 2023 - Eur Respiratory Soc
Pulmonary hypertension (PH) is a prevalent disease of the pulmonary vasculature that is
characterised by considerable morbidity and mortality. Substantial efforts have been made …

The controversial role of beta-blockers in heart failure with preserved ejection fraction

S Wernhart, M Papathanasiou, T Rassaf… - Pharmacology & …, 2023 - Elsevier
Beta-blocker (BB) therapy is a main pillar in treating patients with heart failure and reduced
ejection fraction and has shown a prognostic benefit. However, evidence for application of …

[HTML][HTML] Pathophysiology and treatment of chronic thromboembolic pulmonary hypertension

N Otani, R Watanabe, T Tomoe, S Toyoda… - International Journal of …, 2023 - mdpi.com
Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which an
organic thrombus remains in the pulmonary artery (PA) even after receiving anticoagulation …

[HTML][HTML] Unraveling the epigenetic landscape of pulmonary arterial hypertension: implications for personalized medicine development

J Dave, V Jagana, R Janostiak, M Bisserier - Journal of Translational …, 2023 - Springer
Pulmonary arterial hypertension (PAH) is a multifactorial disease associated with the
remodeling of pulmonary blood vessels. If left unaddressed, PAH can lead to right heart …

Clinical–radiological–pathological correlation in pulmonary arterial hypertension

R Condliffe, C Durrington, A Hameed… - European …, 2023 - Eur Respiratory Soc
Pulmonary hypertension (PH) is defined by the presence of a mean pulmonary arterial
pressure> 20 mmHg. Current guidelines describe five groups of PH with shared …

Epidemiology, pathophysiology, diagnosis and management of chronic right‐sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart …

M Adamo, O Chioncel, M Pagnesi… - European journal of …, 2024 - Wiley Online Library
Right‐sided heart failure and tricuspid regurgitation are common and strongly associated
with poor quality of life and an increased risk of heart failure hospitalizations and death …

[HTML][HTML] New drugs and therapies in pulmonary arterial hypertension

AJ Shah, T Beckmann, M Vorla, DK Kalra - International Journal of …, 2023 - mdpi.com
Pulmonary arterial hypertension is a chronic, progressive disorder of the pulmonary
vasculature with associated pulmonary and cardiac remodeling. PAH was a uniformly fatal …

Pulmonary arterial hypertension: sex matters

JP Dignam, S Sharma, I Stasinopoulos… - British Journal of …, 2024 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …

Sex-biased TGFβ signalling in pulmonary arterial hypertension

M Wits, C Becher, F de Man… - Cardiovascular …, 2023 - academic.oup.com
Pulmonary arterial hypertension (PAH) is a rare cardiovascular disorder leading to
pulmonary hypertension and, often fatal, right heart failure. Sex differences in PAH are …