Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Beyond being aging-related diseases, atherosclerosis and osteoporosis share common
pathogenetic pathways implicated in bone and vascular mineralization. However, the …

The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …

Accumulation of lipid-laden macrophages within the arterial neointima is a critical step in
atherosclerotic plaque formation. Here, we show that reduced levels of the cellular plasticity …

Klotho protein is an anti-aging protein and plays multiple roles in ion-regulation, anti-
oxidative stress, and energy metabolism through various pathways. Metabolic syndrome is a …

The extracellular matrix (ECM) is an intricate network composed of various multi-domain
macromolecules like collagen, proteoglycans, and fibronectin, etc., that form a structurally …

The Wnt signalling pathways are composed of a highly conserved cascade of events that
govern cell differentiation, apoptosis and cell orientation. Three major and distinct Wnt …

We have previously shown that treatment with third-generation antisense oligonucleotides
against miR-494-3p (3GA-494) reduces atherosclerotic plaque progression and stabilizes …

Background Atherosclerosis (AS) is the most common inducer of cardiovascular diseases,
and resveratrol (RSV) has played a protective function in the endothelial injury of AS. This …

The proteins of the Wnt family are involved in a variety of physiological processes by means
of several canonical and noncanonical signaling pathways. Wnt signaling has been recently …