Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers
OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …
of these molecules to regulate genetic activity in different cancers, including colorectal …
Recent advances in DNA origami-engineered nanomaterials and applications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …
engineering, and materials science can elegantly converge. Since the original proposal of …
[HTML][HTML] Functionalization and higher-order organization of liposomes with DNA nanostructures
Small unilamellar vesicles (SUVs) are indispensable model membranes, organelle mimics,
and drug and vaccine carriers. However, the lack of robust techniques to functionalize or …
and drug and vaccine carriers. However, the lack of robust techniques to functionalize or …
Engineering DNA-based cytoskeletons for synthetic cells
K Jahnke, K Göpfrich - Interface Focus, 2023 - royalsocietypublishing.org
The development and bottom-up assembly of synthetic cells with a functional cytoskeleton
sets a major milestone to understand cell mechanics and to develop man-made machines …
sets a major milestone to understand cell mechanics and to develop man-made machines …
DNA-origami line-actants control domain organization and fission in synthetic membranes
Cells can precisely program the shape and lateral organization of their membranes using
protein machinery. Aiming to replicate a comparable degree of control, here we introduce …
protein machinery. Aiming to replicate a comparable degree of control, here we introduce …
DNA origami voltage sensors for transmembrane potentials with single-molecule sensitivity
Signal transmission in neurons goes along with changes in the transmembrane potential. To
report them, different approaches, including optical voltage-sensing dyes and genetically …
report them, different approaches, including optical voltage-sensing dyes and genetically …
Self‐assembly of DNA nanostructures in different cations
The programmable nature of DNA allows the construction of custom‐designed static and
dynamic nanostructures, and assembly conditions typically require high concentrations of …
dynamic nanostructures, and assembly conditions typically require high concentrations of …
A synthetic signaling network imitating the action of immune cells in response to bacterial metabolism
State‐of‐the‐art bottom‐up synthetic biology allows to replicate many basic biological
functions in artificial‐cell‐like devices. To mimic more complex behaviors, however, artificial …
functions in artificial‐cell‐like devices. To mimic more complex behaviors, however, artificial …
Binding of DNA origami to lipids: maximizing yield and switching via strand displacement
JKD Singh, E Darley, P Ridone, JP Gaston… - Nucleic acids …, 2021 - academic.oup.com
Liposomes are widely used as synthetic analogues of cell membranes and for drug delivery.
Lipid-binding DNA nanostructures can modify the shape, porosity and reactivity of …
Lipid-binding DNA nanostructures can modify the shape, porosity and reactivity of …
Engineering DNA nanostructures to manipulate immune receptor signaling and immune cell fates
Immune cells sense, communicate, and logically integrate a multitude of environmental
signals to make important cell‐fate decisions and fulfill their effector functions. These …
signals to make important cell‐fate decisions and fulfill their effector functions. These …