[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Noninvasive respiratory support for adults with acute respiratory failure

L Munshi, J Mancebo, LJ Brochard - New England Journal of …, 2022 - Mass Medical Soc
Noninvasive Respiratory Support in Acute Respiratory Failure Noninvasive respiratory
support can be useful for cardiogenic pulmonary edema and COPD exacerbations. For other …

Evaluation and management of adults with obstructive sleep apnea syndrome

JJ Lee, KM Sundar - Lung, 2021 - Springer
Obstructive sleep apnea syndrome (OSAS) is a common and underdiagnosed medical
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …

[HTML][HTML] How to ventilate obese patients in the ICU

A De Jong, H Wrigge, G Hedenstierna, L Gattinoni… - Intensive care …, 2020 - Springer
Obesity is an important risk factor for major complications, morbidity and mortality related to
intubation procedures and ventilation in the intensive care unit (ICU). The fall in functional …

Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation …

JF Masa, B Mokhlesi, I Benítez, FJG de Terreros… - The Lancet, 2019 - thelancet.com
Background Obesity hypoventilation syndrome is commonly treated with continuous positive
airway pressure or non-invasive ventilation during sleep. Non-invasive ventilation is more …

[HTML][HTML] OSA and chronic respiratory disease: mechanisms and epidemiology

BW Locke, JJ Lee, KM Sundar - International Journal of Environmental …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications
on the outcomes of patients with chronic lung disease. The hallmark of OSA is a collapse of …

[HTML][HTML] Reboxetine plus oxybutynin for OSA treatment: a 1-week, randomized, placebo-controlled, double-blind crossover trial

E Perger, LT Montemurro, D Rosa, S Vicini, M Marconi… - Chest, 2022 - Elsevier
Background The recent discovery that a combination of noradrenergic and antimuscarinic
drugs improved upper airway muscle function during sleep and reduced OSA severity has …

A randomised controlled trial of CPAP versus non-invasive ventilation for initial treatment of obesity hypoventilation syndrome

ME Howard, AJ Piper, B Stevens, AE Holland, BJ Yee… - Thorax, 2017 - thorax.bmj.com
Background Obesity hypoventilation syndrome (OHS) is the most common indication for
home ventilation, although the optimal therapy remains unclear, particularly for severe …

[HTML][HTML] Long-term noninvasive ventilation in the Geneva Lake area: indications, prevalence, and modalities

C Cantero, D Adler, P Pasquina, C Uldry, B Egger… - Chest, 2020 - Elsevier
Background Noninvasive ventilation (NIV) is standard of care for chronic hypercapnic
respiratory failure, but indications, devices, and ventilatory modes are in constant evolution …

Long-term survival following initiation of home non-invasive ventilation: a European study

M Patout, E Lhuillier, G Kaltsakas, A Benattia, J Dupuis… - Thorax, 2020 - thorax.bmj.com
Introduction Although home non-invasive ventilation (NIV) is increasingly used to manage
patients with chronic ventilatory failure, there are limited data on the long-term outcome of …