Current and emerging drug treatment strategies for polycystic ovary syndrome

N Helvaci, BO Yildiz - Expert Opinion on Pharmacotherapy, 2023 - Taylor & Francis
Introduction Polycystic ovary syndrome (PCOS) is a common hormonal, metabolic, and
reproductive disorder with a heterogeneous phenotype. As the exact etiology of PCOS is still …

[HTML][HTML] Utility of matrix metalloproteinases in the diagnosis, monitoring and prognosis of ovarian cancer patients

A Kicman, M Niczyporuk, M Kulesza… - Cancer management …, 2022 - ncbi.nlm.nih.gov
Ovarian cancer is one of the most common gynecologic malignancies. It is characterized by
a high mortality rate, which is mainly due to the asymptomatic course of the disease. In light …

Oral contraceptives, hormone replacement therapy, and stroke risk

T Johansson, P Fowler, WE Ek, A Skalkidou… - Stroke, 2022 - Am Heart Assoc
Background: Millions of women worldwide use exogenous hormones as oral contraceptives
or hormone replacement therapy. Still, time-dependent and long-term consequences of …

Newly diagnosed and relapsed epithelial ovarian cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

A González-Martín, P Harter, A Leary… - Annals of …, 2023 - annalsofoncology.org
Epithelial ovarian cancer (EOC) represents a heterogeneous spectrum of disease entities at
a clinical, pathological and molecular level. Ovarian cancer is the second most lethal …

[HTML][HTML] Hormonal contraception and risk of breast cancer and breast cancer in situ among Swedish women 15–34 years of age: a nationwide register-based study

JN Hultstrand, K Gemzell-Danielsson… - The Lancet Regional …, 2022 - thelancet.com
Background Evidence on a possible association between newer hormonal contraceptives
(HC) and risk of breast cancer remains inconclusive, especially as concerns progestogen …

[HTML][HTML] An update on contraception in polycystic ovary syndrome

SH Oguz, BO Yildiz - Endocrinology and Metabolism, 2021 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged
women, characterized by hyperandrogenism, oligo/anovulation, and polycystic ovarian …

Oral contraceptive use by formulation and breast cancer risk by subtype in the Nurses' Health Study II: a prospective cohort study

NA Burchardt, AH Eliassen, AL Shafrir, B Rosner… - American Journal of …, 2022 - Elsevier
Background Oral contraceptive use has been associated with a higher breast cancer risk;
however, evidence for the associations between different oral contraceptive formulations …

Serum estradiol and 20 site-specific cancers in women: Mendelian randomization study

SC Larsson, S Kar, JRB Perry, P Carter… - The Journal of …, 2022 - academic.oup.com
Context The causal role of endogenous estradiol in cancers other than breast and
endometrial cancer remains unclear. Objective This Mendelian randomization study …

Investigating the effect of estradiol levels on the risk of breast, endometrial, and ovarian cancer

Å Johansson, D Schmitz, J Höglund… - Journal of the …, 2022 - academic.oup.com
Background High levels of estrogen are associated with increased risk of breast and
endometrial cancer and have been suggested to also play a role in the development of …

Associations of Oral Contraceptive Use With Cardiovascular Disease and All‐Cause Death: Evidence From the UK Biobank Cohort Study

W Dou, Y Huang, X Liu, C Huang, J Huang… - Journal of the …, 2023 - Am Heart Assoc
Background The associations of oral contraceptive (OC) use with cardiovascular disease
(CVD) and all‐cause death remains unclear. We aimed to determine the associations of OC …