[HTML][HTML] Cancer cachexia: molecular mechanisms and treatment strategies

T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

[HTML][HTML] Sensing the oxygen and temperature in the adipose tissues–who's sensing what?

GS Kang, HJ Jo, YR Lee, T Oh, HJ Park… - Experimental & Molecular …, 2023 - nature.com
Adipose tissues, composed of various cell types, including adipocytes, endothelial cells,
neurons, and immune cells, are organs that are exposed to dynamic environmental …

The combination of metformin with morin alleviates hepatic steatosis via modulating hepatic lipid metabolism, hepatic inflammation, brown adipose tissue …

SS Tehrani, G Goodarzi, G Panahi, F Zamani-Garmsiri… - Life Sciences, 2023 - Elsevier
Aim The valuable effects of metformin (MET) and morin (MOR) in the improvement of NAFLD
have been proposed, nevertheless, their combination impacts were not investigated so far …

Irisin/PGC-1α/FNDC5 pathway in Parkinson's disease: truth under the throes

NH Ali, NA Alhamdan, HM Al-Kuraishy… - Naunyn-Schmiedeberg's …, 2023 - Springer
Parkinson's disease (PD) is considered one of the most common neurodegenerative brain
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …

[HTML][HTML] Adipose tissue remodeling in obesity: an overview of the actions of thyroid hormones and their derivatives

G Petito, F Cioffi, N Magnacca, P de Lange, R Senese… - Pharmaceuticals, 2023 - mdpi.com
Metabolic syndrome and obesity have become important health issues of epidemic
proportions and are often the cause of related pathologies such as type 2 diabetes (T2DM) …

[HTML][HTML] Receptor for the Advanced Glycation End Products (RAGE) Pathway in Adipose Tissue Metabolism

K Gutowska, K Czajkowski, A Kuryłowicz - International Journal of …, 2023 - mdpi.com
Advanced glycation end products (AGEs) are mediators in the process of cellular
dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of …

[HTML][HTML] Nutraceuticals and the network of obesity modulators

S Ammendola, A Scotto d'Abusco - Nutrients, 2022 - mdpi.com
Obesity is considered an increasingly widespread disease in the world population,
regardless of age and gender. Genetic but also lifestyle-dependent causes have been …

[HTML][HTML] An update on the secretory functions of brown, white, and beige adipose tissue: towards therapeutic applications

Z Ghesmati, M Rashid, S Fayezi, F Gieseler… - Reviews in Endocrine …, 2023 - Springer
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …

Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice

J Kaur, DP Singh, V Kumar, S Kaur, RK Bhunia… - Life Sciences, 2023 - Elsevier
Background & aim Obesity is a worldwide epidemic leading to decreased quality of life,
higher medical expenses and significant morbidity. Enhancing energy expenditure and …

[HTML][HTML] Molecular mechanisms of obesity-induced development of insulin resistance and promotion of amyloid-β accumulation: Dietary therapy using weak organic …

Y Marunaka - Biomolecules, 2023 - mdpi.com
Insulin resistance is one of the etiologies of type 2 diabetes mellitus (T2DM) and has been
suggested to contribute to the development of Alzheimer's disease by promoting amyloid-β …