Objective Both academic medical centers and biomedical research sponsors need to
understand impact of scientific funding to determine value. For the National Institutes of …

Introduction: COVID-19 is a major health threat around the world causing hundreds of
millions of infections and millions of deaths. There is a pressing global need for effective …

Introduction: Clinical trials are a critical step in the meaningful translation of biomedical
discoveries into effective diagnostic and therapeutic interventions. Quality by design (QbD) …

Introduction: The Clinical and Translational Science Awards (CTSA) Consortium, about 60
National Institutes of Health (NIH)-supported CTSA hubs at academic health care institutions …

Identifying and disseminating actionable intelligence is a challenging task that requires
thoughtful planning. The National Center for Advancing Translational Sciences instituted the …

Despite improved knowledge regarding disease causality, new drug targets, and enabling
technologies, the attrition rate for compounds entering clinical trials has remained …

Introduction: The Clinical and Translational Science Awards (CTSA) Consortium, a network
of academic health care institutions with CTSA hubs, is charged with improving the national …

Abstract Quality by Design (QbD) is a contemporary methodology that guarantees the quality
of pharmaceuticals by implementing a methodical and evidence-based approach …

Cognitive psychology has undergone a paradigm shift in the understanding of how
knowledge is acquired and represented. This shift represents a move away from brain …

Failure to accrue participants into clinical trials incurs economic costs, wastes resources,
jeopardizes answering research questions meaningfully, and delays translating research …