Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited

T Watson, E Shantsila, GYH Lip - The Lancet, 2009 - thelancet.com
Atrial fibrillation is the most common sustained cardiac arrhythmia, which is associated with
a high risk of stroke and thromboembolism. Increasing evidence suggests that the …

Left atrial appendage: structure, function, and role in thromboembolism

NM Al-Saady, OA Obel, AJ Camm - Heart, 1999 - heart.bmj.com
The left atrial appendage (LAA) is derived from the left wall of the primary atrium, which
forms during the fourth week of embryonic development. It has developmental …

Left atrial appendage function and stroke risk

S Yaghi, C Song, WA Gray, KL Furie, MSV Elkind… - Stroke, 2015 - Am Heart Assoc
The LAA is the remnant of the embryonic left atrium, whereas the smooth-walled left atrium
originates from the primordial pulmonary vein and its branches. The LAA is largely …

Echocardiographic assessment of the left atrial appendage

Y Agmon, BK Khandheria, F Gentile… - Journal of the American …, 1999 - jacc.org
The left atrial (LA) appendage is a common source of cardiac thrombus formation associated
with systemic embolism. Transesophageal echocardiography allows a detailed evaluation of …

The prothrombotic state in atrial fibrillation: pathophysiological and management implications

AA Khan, GYH Lip - Cardiovascular research, 2019 - academic.oup.com
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is associated with
significant morbidity and mortality. There is plenty of evidence available to support the …

Role of left atrial appendage in left atrial reservoir function as evaluated by left atrial appendage clamping during cardiac surgery

MD Tomotsugu Tabata, MD Takashi Oki… - The American journal of …, 1998 - Elsevier
We evaluated the role of left atrial appendage (LAA) in the left atrial (LA) reservoir function
by assessing the changes in LA flow dynamics after LAA clamping during cardiac surgery …

Atrial stunning: basics and clinical considerations

IA Khan - International journal of cardiology, 2003 - Elsevier
Conversion of atrial fibrillation and flutter to sinus rhythm results in a transient mechanical
dysfunction of atrium and atrial appendage, termed atrial stunning. Atrial stunning has been …

The left atrial appendage: from embryology to prevention of thromboembolism

G Patti, V Pengo, R Marcucci, P Cirillo… - European Heart …, 2017 - academic.oup.com
The left atrial appendage (LAA) is the main source of thromboembolism in patients with non-
valvular atrial fibrillation (AF). As such, the LAA can be the target of specific occluding device …

Cardiac imaging for assessment of left atrial appendage stasis and thrombosis

J Romero, JJ Cao, MJ Garcia, CC Taub - Nature Reviews Cardiology, 2014 - nature.com
Atrial fibrillation (AF) is the most-common arrhythmia in the elderly population (age> 65
years). The left atrial appendage (LAA) is the main location of thrombus formation …

[HTML][HTML] Influence of acutely altered loading conditions on left atrial appendage flow velocities

BD Hoit, Y Shao, M Gabel - Journal of the American College of Cardiology, 1994 - Elsevier
Objectives. The purpose of this study was to identify the effects of altered loading conditions
on left atrial appendage flow velocities. Background. Although studies have suggested that …