Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …

Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex …

Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …

Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …

Whole genome sequencing (WGS) provides the highest resolution for genome-based
species identification and can provide insight into the antimicrobial resistance and virulence …

Background Whole-genome sequencing (WGS) of Mycobacterium tuberculosis complex has
become an important tool in diagnosis and management of drug-resistant tuberculosis …

Antibiotic resistance among bacterial pathogens poses a major global health threat.
Mycobacterium tuberculosis complex (MTBC) is estimated to have the highest resistance …

Tuberculosis (TB), considered an ancient disease, is still killing one person every 21
seconds. Diagnosis of Mycobacterium tuberculosis (M. tb) still has many challenges …