In patients with Parkinson's disease, heterogeneous cholinergic system changes can occur
in different brain regions. These changes correlate with a range of clinical features, both …

The time is ripe to integrate burgeoning evidence of the important role of sensory and motor
functioning in mental health within the National Institute of Mental Health's [NIMH] Research …

Neurodegenerative diseases, for example Alzheimer's, are perceived as driven by
hereditary, cellular, and multifaceted biochemical actions. Numerous plant products, for …

Many advances in understanding the pathophysiology of Parkinson disease (PD) have been
based on research addressing its motor symptoms and phenotypes. Various data-driven …

As alternatives to perfluorooctane sulfonate (PFOS), 6: 2 Cl-PFESA (F-53B) and sodium p-
perfluorous nonenoxybenzene sulfonate (OBS) are frequently detected in aquatic …

There are three neural feedback pathways to the primary visual cortex (V1): corticocortical,
pulvinocortical, and cholinergic. What are the respective functions of these three …

Despite decades of research, we do not definitively know how people sometimes see things
that are not there. Eight models of complex visual hallucinations have been published since …

Synaptic plasticity configures interactions between neurons and is therefore likely to be a
primary driver of behavioral learning and development. How this microscopic-macroscopic …

l-DOPA treatment for Parkinson's disease frequently leads to dyskinesias, the
pathophysiology of which is poorly understood. We used MALDI-MSI to map the distribution …

Until now, a satisfying account of the cause and purpose of migraine has remained elusive.
We explain migraine within the frameworks of allostasis (the situationally-flexible, forward …