Role of biocatalysis in sustainable chemistry

RA Sheldon, JM Woodley - Chemical reviews, 2018 - ACS Publications
Based on the principles and metrics of green chemistry and sustainable development,
biocatalysis is both a green and sustainable technology. This is largely a result of the …

Artificial biocatalytic linear cascades for preparation of organic molecules

JH Schrittwieser, S Velikogne, M Hall… - Chemical …, 2018 - ACS Publications
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

[HTML][HTML] Transaminase biocatalysis: optimization and application

F Guo, P Berglund - Green Chemistry, 2017 - pubs.rsc.org
Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …

Bioremediation 3.0: engineering pollutant-removing bacteria in the times of systemic biology

P Dvořák, PI Nikel, J Damborský, V de Lorenzo - Biotechnology advances, 2017 - Elsevier
Elimination or mitigation of the toxic effects of chemical waste released to the environment
by industrial and urban activities relies largely on the catalytic activities of microorganisms …

Application of ω-transaminases in the pharmaceutical industry

SA Kelly, S Pohle, S Wharry, S Mix, CCR Allen… - Chemical …, 2018 - ACS Publications
Chiral amines are valuable building blocks for the pharmaceutical industry. ω-TAms have
emerged as an exciting option for their synthesis, offering a potential “green alternative” to …

CLEAs, combi-CLEAs and 'smart'magnetic CLEAs: Biocatalysis in a bio-based economy

RA Sheldon - Catalysts, 2019 - mdpi.com
Biocatalysis has emerged in the last decade as a pre-eminent technology for enabling the
envisaged transition to a more sustainable bio-based economy. For industrial viability it is …

Multi‐enzymatic cascade reactions: overview and perspectives

E Ricca, B Brucher… - Advanced Synthesis & …, 2011 - Wiley Online Library
Multi‐enzymatic cascade reactions, ie, the combination of several enzymatic transformations
in concurrent one‐pot processes, offer considerable advantages: the demand of time, costs …

The fourth wave of biocatalysis is approaching

UT Bornscheuer - … Transactions of the Royal Society A …, 2018 - royalsocietypublishing.org
Biocatalysis has undergone a tremendous development in the past few years. A plethora of
methods enable the rather rapid tailored-design of an enzyme for a targeted reaction such …

A retrosynthesis approach for biocatalysis in organic synthesis

ROMA de Souza, LSM Miranda… - … –A European Journal, 2017 - Wiley Online Library
For the planning of an organic synthesis route, the disconnection approach guided by
retrosynthetic analysis of possible intermediates and the chemical reactions involved, back …

Enzymatic reductions for the chemist

F Hollmann, IWCE Arends, D Holtmann - Green Chemistry, 2011 - pubs.rsc.org
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …