Microglia, the brain's immune sentinels, have garnered much attention in recent years.
Researchers have begun to identify the manifold roles that these cells play in the central …

Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of
systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion …

Microglia are the principal resident immune cells in the central nervous system and are
believed to be versatile players in both inflammatory and physiological contexts. On the one …

Abstract Colony-stimulating factor-1 receptor (CSF-1R), also known as FMS kinase, is a type
I single transmembrane protein mainly expressed in myeloid cells, such as monocytes …

Spinal cord injury (SCI) induces a pronounced neuroinflammation driven by activation and
proliferation of resident microglia as well as infiltrating peripheral monocyte-derived …

Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman
primates - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Microglia are prominent immune cells in the central nervous system (CNS) and are critical
players in both neurological development and homeostasis, and in neurological diseases …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by
autoantibody production and multiple organ damage. Toll-like receptor 7 (TLR7), an innate …