Endogenous indole and its derivatives (indoles), considered as promising N-substituted
heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and …

Extracorporeal Kidney-Replacement Therapy for AKI Acute kidney injury can be
accompanied by life-threatening electrolyte and metabolic abnormalities. Kidney …

The microbes and microbial pathways that influence host inflammatory disease progression
remain largely undefined. Here, we show that variation in atherosclerosis burden is partially …

Biocompatibility in hemodialysis (HD) has considerably improved in recent decades, but
remains an open issue to be solved, appearing essential to reduce systemic inflammation …

Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to
the average population, and this is partially due to the plasma accumulation of solutes …

In recent years, more scientific data have pointed out the close connection between
intestinal microbial community, nutritional habits, lifestyle, and the appearance of various …

Aims Myocardial infarction (MI) is a major cause of death and disability worldwide. Most
metabolomics studies investigating metabolites predicting MI are limited by the participant …

Edema caused by kidney disease is called renal edema. Edema is a common symptom of
many human kidney diseases. Patients with renal edema often need to take diuretics …

Blood purification is a commonly used method to remove excess metabolic waste in the
blood in renal replacement therapy. The sufficient removal of these toxins from blood can …

Ferroptosis is a cell death mechanism characterized by intracellular iron accumulation and
lipid peroxidation. Effects of uremic toxins on ferroptosis in the kidney are not well …