The function of the mammalian heart depends on the interplay between different cardiac cell
types. The deployment of these cells, with precise spatiotemporal regulation, is also …

The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and
cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the …

Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to
come from the lateral plate mesoderm despite experimental evidence for a broader source …

The origin and early diversification of jawed vertebrates involved major changes to skeletal
and soft anatomy. Skeletal transformations can be examined directly by studying fossil stem …

During vertebrate heart development, two progenitor populations, first and second heart
fields (FHF, SHF), sequentially contribute to longitudinal subdivisions of the heart tube (HT) …

The arterial and venous poles of the mammalian heart are hotspots of congenital heart
defects (CHD) such as those observed in 22q11. 2 deletion (or DiGeorge) and Holt–Oram …

In vertebrates, head and trunk muscles develop from different mesodermal populations and
are regulated by distinct genetic networks. Neck muscles at the head-trunk interface remain …

In vertebrates, multipotent progenitors located in the pharyngeal mesoderm form
cardiomyocytes and branchiomeric head muscles, but the dynamic gene expression …

Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma that histologically resembles
embryonic skeletal muscle. RMS occurs throughout the body and an exclusively myogenic …

The poles of the heart and branchiomeric muscles of the face and neck are formed from the
cardiopharyngeal mesoderm within the pharyngeal apparatus. They are disrupted in …