Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance

MJ Reddehase - Nature Reviews Immunology, 2002 - nature.com
CD8+ T cells are the main effector cells for the immune control of cytomegaloviruses. To
subvert this control, human and mouse cytomegaloviruses each encode a set of immune …

Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

CD Mol, AS Arvai, G Slupphaug, B Kavli, I Alseth… - Cell, 1995 - cell.com
Crystal structures of the DNA repair enzyme human uraciI-DNA glycosylase (UDG),
combined with mutational analysis, reveal the structural basis for the specificity of the …

Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene

D Yu, GA Smith, LW Enquist, T Shenk - Journal of virology, 2002 - Am Soc Microbiol
The full-length genome of human cytomegalovirus strain AD169 was cloned as an infectious
bacterial artificial chromosome (BAC) plasmid, pAD/Cre. The BAC vector, flanked by LoxP …

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

F Kern, T Bunde, N Faulhaber, F Kiecker… - The Journal of …, 2002 - academic.oup.com
Antigen-specific, cytokine flow cytometry was used to analyze the prevalence and frequency
of CD4 and CD8 memory T cells specific for the abundantly expressed cytomegalovirus …

Fast screening procedures for random transposon libraries of cloned herpesvirus genomes: mutational analysis of human cytomegalovirus envelope glycoprotein …

U Hobom, W Brune, M Messerle, G Hahn… - Journal of …, 2000 - Am Soc Microbiol
We have cloned the human cytomegalovirus (HCMV) genome as an infectious bacterial
artificial chromosome (BAC) in Escherichia coli. Here, we have subjected the HCMV BAC to …

Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells

B Bodaghi, TR Jones, D Zipeto, C Vita, L Sun… - The Journal of …, 1998 - rupress.org
Human cytomegalovirus (HCMV), a betaherpesvirus, has developed several ways to evade
the immune system, notably downregulation of cell surface expression of major …

Viral immune evasion: a masterpiece of evolution

MT Vossen, EM Westerhout, C Söderberg-Nauclér… - Immunogenetics, 2002 - Springer
Coexistence of viruses and their hosts imposes an evolutionary pressure on both the virus
and the host immune system. On the one hand, the host has developed an immune system …

The interacting UL31 and UL34 gene products of pseudorabies virus are involved in egress from the host-cell nucleus and represent components of primary …

W Fuchs, BG Klupp, H Granzow, N Osterrieder… - Journal of …, 2002 - Am Soc Microbiol
ABSTRACT A 2.6-kbp fragment of the pseudorabies virus (PrV) genome was sequenced
and shown to contain the homologues of the highly conserved herpesvirus genes UL31 and …

Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals.

K Kondo, J Xu, ES Mocarski - Proceedings of the National …, 1996 - National Acad Sciences
Following infection with cytomegalovirus, human granulocyte-macrophage progenitors carry
the viral genome but fail to support productive replication. Viral transcripts arise from a …

Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication

GS Pari, DG Anders - Journal of virology, 1993 - Am Soc Microbiol
Recently we described the use of human cytomegalovirus (HCMV) cosmid clones in a
cotransfection assay of HCMV oriLyt replication (GS Pari, MA Kacica, and DG Anders, J …