Critical analysis of the effects of SGLT2 inhibitors on renal tubular sodium, water and chloride homeostasis and their role in influencing heart failure outcomes

M Packer, CS Wilcox, JM Testani - Circulation, 2023 - Am Heart Assoc
SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose
and sodium in the early proximal renal tubule, but the magnitude and duration of any …

[HTML][HTML] Edema formation in congestive heart failure and the underlying mechanisms

Z Abassi, EE Khoury, T Karram… - Frontiers in cardiovascular …, 2022 - frontiersin.org
Congestive heart failure (HF) is a complex disease state characterized by impaired
ventricular function and insufficient peripheral blood supply. The resultant reduced blood …

[HTML][HTML] Suppression of Cardiogenic Edema with Sodium–Glucose Cotransporter-2 Inhibitors in Heart Failure with Reduced Ejection Fraction: Mechanisms and …

RD Sullivan, ME McCune, M Hernandez, GL Reed… - Biomedicines, 2022 - mdpi.com
In heart failure with reduced ejection fraction (HFrEF), cardiogenic edema develops from
impaired cardiac function, pathological remodeling, chronic inflammation, endothelial …

[HTML][HTML] Strategies in activating lymphatic system on symptom distress and health-related quality of life in patients with heart failure: secondary analysis of a pilot …

R Liu, J Fang, MR Fu, Q Meng, M Li… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background Abnormal interstitial fluid accumulation remains the major cause for patients
with heart failure (HF) to endure a myriad of distressing symptoms and a decline in their …

Harnessing the Eccrine Sweat Glands for the Management of Interdialytic Weight Gain–A Pilot Study

ZA Armaly, Y Nitzan, G Chernin, D Aronson - medRxiv, 2024 - medrxiv.org
Background Hemodialysis patients are susceptible to excess volume accumulation,
particularly over the 2-day interval (long interdialytic gap), resulting in higher interdialytic …

Biomarker assessment of lymphatic system remodeling in acute heart failure

HM Salah, P Alvarez - Journal of cardiac failure, 2023 - pubmed.ncbi.nlm.nih.gov
Biomarker Assessment of Lymphatic System Remodeling in Acute Heart Failure Biomarker
Assessment of Lymphatic System Remodeling in Acute Heart Failure J Card Fail. 2023 Dec;29(12):1639-1641 …