Depicting the molecular features of suicidal behavior: A review from an “omics” perspective

CA Pereira, G Reis-de-Oliveira, BC Pierone… - Psychiatry …, 2023 - Elsevier
Background: Suicide is one of the leading global causes of death. Behavior patterns from
suicide ideation to completion are complex, involving multiple risk factors. Advances in …

Integrative transcriptome-and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls

Q Sha, Z Fu, ML Escobar Galvis, Z Madaj… - Molecular …, 2024 - nature.com
Suicide rates have increased steadily world-wide over the past two decades, constituting a
serious public health crisis that creates a significant burden to affected families and the …

Associations of potential plasma biomarkers with suicide attempt history, current suicidal ideation and subsequent suicidal events in patients with depression: a …

A Lengvenyte, R Belzeaux, E Olié… - Brain, behavior, and …, 2023 - Elsevier
A growing body of evidences suggests that suicidal ideation (SI) and suicidal behaviors
have biological bases. However, no biological marker is currently available to evaluate the …

Associations of the immune system in aggression traits and the role of microglia as mediators

A Takahashi - Neuropharmacology, 2024 - Elsevier
There is an important relationship between the immune system and aggressive behavior.
Aggressive encounters acutely increase the levels of proinflammatory cytokines, and there …

The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder

H Namkung, H Yukitake, D Fukudome, BJ Lee, M Tian… - Neuron, 2023 - cell.com
Schizophrenia (SZ) and bipolar disorder (BP) are highly heritable major psychiatric
disorders that share a substantial portion of genetic risk as well as their clinical …

Integrative analyses of scRNA-seq, bulk mRNA-seq, and DNA methylation profiling in depressed suicide brain tissues

Y Zhou, L Xiong, J Chen✉… - International journal of …, 2023 - academic.oup.com
Background Suicidal behaviors have become a serious public health concern globally due
to the economic and human cost of suicidal behavior to individuals, families, communities …

Alcohol use disorder and risk of specific methods of suicide death in a national cohort

AC Edwards, L Abrahamsson, C Crump… - Acta Psychiatrica …, 2024 - Wiley Online Library
Introduction Alcohol use disorder (AUD) is among the strongest correlates of suicide death,
but it is unclear whether AUD status is differentially associated with risk of suicide by …

Metabolic features of treatment-refractory major depressive disorder with suicidal ideation

LA Pan, JC Naviaux, L Wang, K Li, JM Monk… - Translational …, 2023 - nature.com
Peripheral blood metabolomics was used to gain chemical insight into the biology of
treatment-refractory Major Depressive Disorder with suicidal ideation, and to identify …

Investigating the clinical profile of suicide attempters who used a violent suicidal means

M Lübbert, L Bahlmann, T Sobanski, A Schulz… - Journal of clinical …, 2022 - mdpi.com
In our study, we aimed to explore the profile of the high-risk subgroup of suicide attempters
that used a violent means compared to suicide attempters that chose a non-violent suicide …

New insights into suicidal behavior from large multi-ancestry genetic meta-analysis

EB Binder - American journal of psychiatry, 2023 - Am Psychiatric Assoc
Suicide is the second leading cause of death among 15-to 29-year-olds (1), and a history of
psychiatric disorders is one of the main risk factors. Hence, understanding the causes of and …