Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …

Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs),
often stay in a state of pathological inflammation and suffer from persistent infection, excess …

Summary β‐site amyloid precursor protein cleaving enzyme‐1 (BACE1) research has
historically focused on its actions as the β‐secretase responsible for the production of β …

Nitric Oxide (NO) is a potent signaling molecule involved in the regulation of various cellular
mechanisms and pathways under normal and pathological conditions. NO production, its …

The final outcome of diabetes is chronic complications, of which vascular complications are
the most serious, which is the main cause of death for diabetic patients and the direct cause …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

Reactive oxygen species (ROS) are not only harmful to cell survival but also essential to cell
signaling through cysteine-based redox switches. In fact, ROS triggers the potential …

Nitric oxide can interact with a wide range of proteins including many that are involved in
metabolism. In this review we have summarized the effects of NO on glycolysis, fatty acid …