[HTML][HTML] Retinal stem cell transplantation: Balancing safety and potential
Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
Advances in biomedical and pharmaceutical applications of functional bacterial cellulose-based nanocomposites
Bacterial cellulose (BC) synthesized by certain species of bacteria, is a fascinating
biopolymer with unique physical and mechanical properties. BC's applications range from …
biopolymer with unique physical and mechanical properties. BC's applications range from …
Consequences of oxidative stress in age-related macular degeneration
SG Jarrett, ME Boulton - Molecular aspects of medicine, 2012 - Elsevier
The retina resides in an environment that is primed for the generation of reactive oxygen
species (ROS) and resultant oxidative damage. The retina is one of the highest oxygen …
species (ROS) and resultant oxidative damage. The retina is one of the highest oxygen …
[HTML][HTML] Stem cell treatment of degenerative eye disease
Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
[HTML][HTML] Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction
AKL Chen, S Reuveny, SKW Oh - Biotechnology advances, 2013 - Elsevier
Mesenchymal stem cells (MSCs) have recently made significant progress with multiple
clinical trials targeting modulation of immune responses, regeneration of bone, cartilage …
clinical trials targeting modulation of immune responses, regeneration of bone, cartilage …
Cell-based therapy technology classifications and translational challenges
NM Mount, SJ Ward, P Kefalas… - … Transactions of the …, 2015 - royalsocietypublishing.org
Cell therapies offer the promise of treating and altering the course of diseases which cannot
be addressed adequately by existing pharmaceuticals. Cell therapies are a diverse group …
be addressed adequately by existing pharmaceuticals. Cell therapies are a diverse group …
[HTML][HTML] Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat
AJ Carr, AA Vugler, ST Hikita, JM Lawrence, C Gias… - PloS one, 2009 - journals.plos.org
Transformation of somatic cells with a set of embryonic transcription factors produces cells
with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent …
with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent …
Stem cells in retinal regeneration: past, present and future
Stem cell therapy for retinal disease is under way, and several clinical trials are currently
recruiting. These trials use human embryonic, foetal and umbilical cord tissue-derived stem …
recruiting. These trials use human embryonic, foetal and umbilical cord tissue-derived stem …
[HTML][HTML] Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells
M Idelson, R Alper, A Obolensky, E Ben-Shushan… - Cell stem cell, 2009 - cell.com
Dysfunction and loss of retinal pigment epithelium (RPE) leads to degeneration of
photoreceptors in age-related macular degeneration and subtypes of retinitis pigmentosa …
photoreceptors in age-related macular degeneration and subtypes of retinitis pigmentosa …
Stem cell based therapies for age-related macular degeneration: the promises and the challenges
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …