[HTML][HTML] Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease

D Bairamian, S Sha, N Rolhion, H Sokol… - Molecular …, 2022 - Springer
Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …

Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases

Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …

Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Gut-derived β-amyloid: Likely a centerpiece of the gut–brain axis contributing to Alzheimer's pathogenesis

J Jin, Z Xu, L Zhang, C Zhang, X Zhao, Y Mao… - Gut …, 2023 - Taylor & Francis
Peripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the
formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on …

Is Alzheimer's disease an infectious neurological disease? A review of the literature

O Uwishema, A Mahmoud, J Sun… - Brain and …, 2022 - Wiley Online Library
Introduction Alzheimer's disease (AD) is a leading cause of dementia around the globe. Its
pathogenesis is characterized primarily by the extracellular deposition of amyloid β peptides …

[HTML][HTML] The gut-brain vascular axis in neuroinflammation

S Carloni, M Rescigno - Seminars in immunology, 2023 - Elsevier
The multifaceted microbiota characterizing our gut plays a crucial role in maintaining
immune, metabolic and tissue homeostasis of the intestine as well as of distal organs …

[HTML][HTML] Gut microbiota, an additional hallmark of human aging and neurodegeneration

N Molinero, A Antón-Fernández, F Hernández, J Ávila… - Neuroscience, 2023 - Elsevier
Gut microbiota represents a diverse and dynamic population of microorganisms harbouring
the gastrointestinal tract, which influences host health and disease. Bacterial colonization of …

[HTML][HTML] Myelin in Alzheimer's disease: culprit or bystander?

M Maitre, H Jeltsch-David, NG Okechukwu… - Acta Neuropathologica …, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …

[HTML][HTML] Treadmill exercise modulates intestinal microbes and suppresses LPS displacement to alleviate neuroinflammation in the brains of APP/PS1 mice

S Yuan, J Yang, Y Jian, Y Lei, S Yao, Z Hu, X Liu… - Nutrients, 2022 - mdpi.com
Neuroinflammation occurs throughout the pathogenesis of Alzheimer's disease (AD). Here,
we investigated the effects of treadmill exercise on neuroinflammation in APP/PS1 …

[HTML][HTML] Gut-brain axis through the lens of gut microbiota and their relationships with Alzheimer's disease pathology: review and recommendations

L Krishaa, TKS Ng, HN Wee, J Ching - Mechanisms of Ageing and …, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people
worldwide. Growing evidence suggests that the gut microbiome (GM) plays a pivotal role in …