[HTML][HTML] Viral hepatitis update: Progress and perspectives
MB Pisano, CG Giadans, DM Flichman… - World journal of …, 2021 - ncbi.nlm.nih.gov
Viral hepatitis, secondary to infection with hepatitis A, B, C, D, and E viruses, are a major
public health problem and an important cause of morbidity and mortality. Despite the huge …
public health problem and an important cause of morbidity and mortality. Despite the huge …
VH1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design
Broadly neutralizing antibodies (bnAbs) are potential therapeutic molecules and valuable
tools for studying conserved viral targets for vaccine and drug design. Interestingly, antibody …
tools for studying conserved viral targets for vaccine and drug design. Interestingly, antibody …
[HTML][HTML] Host genetic determinants of hepatitis B virus infection
Z Zhang, C Wang, Z Liu, G Zou, J Li, M Lu - Frontiers in genetics, 2019 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is still a major health problem worldwide. Recently,
a great number of genetic studies based on single nucleotide polymorphisms (SNPs) and …
a great number of genetic studies based on single nucleotide polymorphisms (SNPs) and …
Immunopathogenesis of HBV infection
J Wu, M Han, J Li, X Yang, D Yang - Hepatitis B Virus Infection: Molecular …, 2020 - Springer
More than 95% of adult infected with HBV show acute self-limited infection and eventually
eliminate the virus. In contrast, about 90% of people exposed to HBV in early childhood …
eliminate the virus. In contrast, about 90% of people exposed to HBV in early childhood …
[HTML][HTML] Hepatitis B virus molecular epidemiology, host-virus interaction, coinfection, and laboratory diagnosis in the MENA region: An update
Hepatitis B virus (HBV) is an enveloped partial double-stranded DNA virus that can cause
acute and chronic hepatitis. According to the World Health Organization (WHO) and the …
acute and chronic hepatitis. According to the World Health Organization (WHO) and the …
[HTML][HTML] Unique features of hepatitis B virus-related hepatocellular carcinoma in pathogenesis and clinical significance
SH Wang, SH Yeh, PJ Chen - Cancers, 2021 - mdpi.com
Simple Summary Hepatitis B virus (HBV) infection is the major risk factor for hepatocellular
carcinoma (HCC). Understanding the unique features for HBV-induced HCC can shed new …
carcinoma (HCC). Understanding the unique features for HBV-induced HCC can shed new …
Large‐scale genome‐wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank
YH Huang, SF Liao, SS Khor, YJ Lin… - Alimentary …, 2020 - Wiley Online Library
Background Chronic hepatitis B virus (HBV) infection is a great health burden with
geographical variations. Aims To explore genetic variants associated with chronic HBV …
geographical variations. Aims To explore genetic variants associated with chronic HBV …
[HTML][HTML] Conventional and genetic risk factors for chronic hepatitis B virus infection in a community-based study of 0.5 million Chinese adults
Despite universal vaccination of newborns, the prevalence of chronic hepatitis virus B (HBV)
infection and the associated disease burden remain high among adults in China. We …
infection and the associated disease burden remain high among adults in China. We …
[HTML][HTML] METTL16 regulates m6A methylation on chronic hepatitis B associated gene HLA-DPB1 involved in liver fibrosis
H Gao, X Wang, H Ma, S Lin, D Zhang, W Wu… - Frontiers in …, 2022 - frontiersin.org
The role of genetic factors in the occurrence and progression of CHB (CHB) is still not fully
explored. In recent years, genome-wide association studies on CHB patients have …
explored. In recent years, genome-wide association studies on CHB patients have …
[HTML][HTML] High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response
How human genetic variation contributes to vaccine effectiveness in infants is unclear, and
data are limited on these relationships in populations with African ancestries. We undertook …
data are limited on these relationships in populations with African ancestries. We undertook …