Detrimental interactions of hypoxia and complement MASP-1 in endothelial cells as a model for atherosclerosis-related diseases

F Demeter, Z Németh, E Kajdácsi, G Bihari, J Dobó… - Scientific Reports, 2024 - nature.com
Both hypoxia and the complement lectin pathway (CLP) are involved in atherosclerosis and
atherosclerosis-related stroke and acute myocardial infarction (AMI). We have previously …

[HTML][HTML] Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease

G Isayeva, K Rumora, E Potlukova, JP Leibfarth… - Clinica Chimica …, 2024 - Elsevier
Background This study aimed to evaluate the diagnostic and prognostic potential of MAp19,
a regulating component of the lectin pathway of the complement system, in patients with …

Systematic analysis of MASP-1 serves as a novel immune-related biomarker in sepsis and trauma followed by preliminary experimental validation

L Xian, S Cheng, W Chen, C Zhong, Z Hu… - Frontiers in …, 2024 - frontiersin.org
Background Dysregulated immune response in trauma and sepsis leads to the abnormal
activation of the complement and coagulation systems. Mannose-binding lectin (MBL) …