Asthma risk factors

E Toskala, DW Kennedy - International forum of allergy & …, 2015 - Wiley Online Library
Background Bronchial asthma is one of the most common chronic diseases in childhood,
with a current prevalence of 6% to 9%, but a prevalence that is increasing at an alarming …

[HTML][HTML] The genetic and epigenetic landscapes of the epithelium in asthma

F Moheimani, ACY Hsu, AT Reid, T Williams, A Kicic… - Respiratory …, 2016 - Springer
Asthma is a global health problem with increasing prevalence. The airway epithelium is the
initial barrier against inhaled noxious agents or aeroallergens. In asthma, the airway …

Genetic polymorphisms and associated susceptibility to asthma

ME March, PMA Sleiman… - International journal of …, 2013 - Taylor & Francis
As complex common diseases, asthma and allergic diseases are caused by the interaction
of multiple genetic variants with a variety of environmental factors. Candidate-gene studies …

[HTML][HTML] Modulatory mechanisms and multiple functions of somatodendritic A-type K+ channel auxiliary subunits

HH Jerng, PJ Pfaffinger - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Auxiliary subunits are non-conducting, modulatory components of the multi-protein ion
channel complexes that underlie normal neuronal signaling. They interact with the pore …

[HTML][HTML] The genetics of asthma and allergic disorders

ME March, PMA Sleiman… - Discovery …, 2011 - discoverymedicine.com
Asthma and allergic diseases are complex conditions caused by a combination of genetic
and environmental factors. More than 100 genes have been associated with asthma and …

[HTML][HTML] CD26 and asthma: a comprehensive review

JJ Nieto-Fontarigo, FJ González-Barcala… - Clinical Reviews in …, 2019 - Springer
Asthma is a heterogeneous and chronic inflammatory family of disorders of the airways with
increasing prevalence that results in recurrent and reversible bronchial obstruction and …

Allergic manifestations in autoimmune gastrointestinal disorders

CM Rossi, MV Lenti, S Merli, G Santacroce… - Autoimmunity …, 2022 - Elsevier
Allergic disorders target a young population, are increasing in both incidence and
prevalence and are associated with significant disease burden. They result from the …

[HTML][HTML] Expression analysis of asthma candidate genes during human and murine lung development

E Melén, AT Kho, S Sharma, R Gaedigk, JS Leeder… - Respiratory …, 2011 - Springer
Background Little is known about the role of most asthma susceptibility genes during human
lung development. Genetic determinants for normal lung development are not only important …

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10–Pulmonary Function Association

J Xu, NC Gaddis, TM Bartz, R Hou… - American journal of …, 2019 - atsjournals.org
Rationale: Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have anti-inflammatory
properties that could benefit adults with comprised pulmonary health. Objective: To …

A polymorphism in HLA-G modifies statin benefit in asthma

D Naidoo, AC Wu, MH Brilliant, J Denny… - The …, 2015 - nature.com
Several reports have shown that statin treatment benefits patients with asthma; however,
inconsistent effects have been observed. The mir-152 family (148a, 148b and 152) has been …