Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

[HTML][HTML] Nutrition and metabolic adaptations in physiological and complicated pregnancy: focus on obesity and gestational diabetes

S Parrettini, A Caroli, E Torlone - Frontiers in endocrinology, 2020 - frontiersin.org
Pregnancy offers a window of opportunity to program the future health of both mothers and
offspring. During gestation, women experience a series of physical and metabolic …

Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

[HTML][HTML] Maternal obesity and risk of low birth weight, fetal growth restriction, and macrosomia: multiple analyses

M Lewandowska - Nutrients, 2021 - mdpi.com
The associations between maternal pre-pregnancy obesity and low birth weight (LBW,<
2500 g) remain inconclusive. Therefore, birth weight in a Polish prospective cohort of 912 …

Improving pregnancy outcomes in humans through studies in sheep

JL Morrison, MJ Berry, KJ Botting… - American Journal …, 2018 - journals.physiology.org
Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …

Regulation of maternal–fetal metabolic communication

CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

[HTML][HTML] Relationship between maternal vitamin D levels and adverse outcomes

H Zhang, S Wang, L Tuo, Q Zhai, J Cui, D Chen, D Xu - Nutrients, 2022 - mdpi.com
Vitamin D (VD), a fat-soluble vitamin, has a variety of functions that are important for growth
and development, including regulation of cell differentiation and apoptosis, immune system …

Placental function and the development of fetal overgrowth and fetal growth restriction

JH Dumolt, TL Powell… - Obstetrics and Gynecology …, 2021 - obgyn.theclinics.com
The developing fetus undergoes a dynamic period of rapid growth that is responsive to
changes in the in utero environment that may contribute to the development of fetal growth …

Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

OR Vaughan, K Maksym, E Silva, K Barentsen… - Clinical …, 2021 - portlandpress.com
Fetal growth restriction (FGR) is a complication of pregnancy that reduces birth weight,
markedly increases infant mortality and morbidity and is associated with later-life …

A narrative review of placental contribution to adverse pregnancy outcomes in women with polycystic ovary syndrome

AS Kelley, YR Smith… - The Journal of Clinical …, 2019 - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of
reproductive-aged women. In pregnancy, women with PCOS experience increased risk of …