mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …

Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

Humans commonly have low level antibodies to poly (ethylene) glycol (PEG) due to
environmental exposure. Lipid nanoparticle (LNP) mRNA vaccines for SARS-CoV-2 contain …

In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid
nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of …

Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

The therapeutic potential for messenger RNA (mRNA) in infectious diseases and cancer
was first realized almost three decades ago, but only in 2018 did the first lipid nanoparticle …

With advances in sequencing and instrument technology, bioinformatics analysis is being
applied to batches of massive cells at single-cell resolution. High-throughput single-cell …

Hereditary genetic diseases, cancer, and infectious diseases are affecting global health and
become major health issues, but the treatment development remains challenging. Gene …

During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …