Mechanisms of dyspnea

NK Burki, LY Lee - Chest, 2010 - Elsevier
The mechanisms and pathways of the sensation of dyspnea are incompletely understood,
but recent studies have provided some clarification. Studies of patients with cord transection …

The antidepressant mechanism of action of vagus nerve stimulation: Evidence from preclinical studies

A Grimonprez, R Raedt, C Baeken, P Boon… - … & Biobehavioral Reviews, 2015 - Elsevier
Vagus nerve stimulation (VNS) is a proposed neuromodulatory treatment for medically
refractory major depression. Although VNS is already used in clinical practice, the …

Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat

GC Hofmann, EM Hasser… - American Journal of …, 2021 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the initial site of integration of sensory information from
the cardiorespiratory system and contributes to reflex responses to hypoxia. Afferent fibers of …

Withdrawal and restoration of central vagal afferents within the dorsal vagal complex following subdiaphragmatic vagotomy

JH Peters, ZR Gallaher, V Ryu… - Journal of Comparative …, 2013 - Wiley Online Library
Vagotomy, a severing of the peripheral axons of the vagus nerve, has been extensively
utilized to determine the role of vagal afferents in viscerosensory signaling. Vagotomy is also …

Exercise training to reduce sympathetic nerve activity in heart failure patients. A systematic review and meta-analysis

MJ Saavedra, F Romero, J Roa… - Brazilian Journal of …, 2018 - Elsevier
Objective To determine the effects of exercise training on sympathetic nerve activity in heart
failure patients. Methods A systematic review was performed. An electronic search of …

Vagotomy blunts cardiorespiratory responses to vagal afferent stimulation via pre‐and postsynaptic effects in the nucleus tractus solitarii

GC Hofmann, P Gama de Barcellos Filho… - The Journal of …, 2024 - Wiley Online Library
Viscerosensory information travels to the brain via vagal afferents, where it is first integrated
within the brainstem nucleus tractus solitarii (nTS), a critical contributor to cardiorespiratory …

Modeling and simulation of vagal afferent input of the cough reflex

L Martvon, M Veternik, M Simera, Z Kotmanova… - Respiratory Physiology …, 2022 - Elsevier
We employed computational modeling to investigate previously conducted experiments of
the effect of vagal afferent modulation on the cough reflex in an anesthetized cat animal …

Chronic Vagotomy Induces nTS Glial Activation, Reduced Glutamatergic Signaling, and Blunted Cardiorespiratory Responses

GC Hofmann - 2023 - search.proquest.com
The brainstem nucleus tractus solitarii (nTS) is the first site of integration of viscerosensory
information provided by afferents of the vagus nerves. The nTS critically contributes to …

Silencing the vagus nerve produces homeostatic changes at second order nucleus tractus solitarius synapses

JB Swartz - 2010 - search.proquest.com
Many diseases, pathologies and medical treatments alter vagal nerve activity, but the
underlying central nervous system changes caused by these treatments are not well …