The main molecular mechanisms underlying methamphetamine-induced neurotoxicity and implications for pharmacological treatment

X Yang, Y Wang, Q Li, Y Zhong, L Chen… - Frontiers in molecular …, 2018 - frontiersin.org
Methamphetamine (METH) is a popular new-type psychostimulant drug with complicated
neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the …

[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies

P Shrestha, N Katila, S Lee, JH Seo, JH Jeong… - Biomedicine & …, 2022 - Elsevier
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

Pharmacological treatments for methamphetamine addiction: current status and future directions

J Ballester, G Valentine, M Sofuoglu - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Methamphetamine (MA) abuse remains a global health challenge despite
intense research interest in the development of pharmacological treatments. This review …

Molecular mechanisms and treatment strategies for methamphetamine‑induced neurodegeneration, inflammation and neurotoxicity

S Omidvari, Z Azimzadeh, F Rashnoo… - Acta neurobiologiae …, 2023 - ane.pl
Methamphetamine (METH) is a highly addictive psychostimulant known for its profound
impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by …

Pharmacotherapeutic agents in the treatment of methamphetamine dependence

KC Morley, JL Cornish, A Faingold… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Methamphetamine use is a serious public health concern in many countries
and is second to cannabis as the most widely abused illicit drug in the world. Effective …

Oxytocin and rodent models of addiction

KC Leong, S Cox, C King, H Becker… - International review of …, 2018 - Elsevier
Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats

S Kohli, MV King, S Williams, A Edwards… - …, 2019 - nature.com
The pituitary neuropeptide oxytocin promotes social behavior, and is a potential adjunct
therapy for social deficits in schizophrenia and autism. Oxytocin may mediate pro-social …

Effect of early life social adversity on drug abuse vulnerability: Focus on corticotropin-releasing factor and oxytocin

MT Bardo, LR Hammerslag, SG Malone - Neuropharmacology, 2021 - Elsevier
Early life adversity can set the trajectory for later psychiatric disorders, including substance
use disorders. There are a host of neurobiological factors that may play a role in the …

Psychoactive drugs—from chemical structure to oxidative stress related to dopaminergic neurotransmission. A review

G Jîtcă, BE Ősz, A Tero-Vescan, CE Vari - Antioxidants, 2021 - mdpi.com
Nowadays, more and more young people want to experience illegal, psychoactive
substances, without knowing the risks of exposure. Besides affecting social life …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …