The inflated significance of neutral genetic diversity in conservation genetics
JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
Mutation bias and adaptation in bacteria
Genetic mutation, which provides the raw material for evolutionary adaptation, is largely a
stochastic force. However, there is ample evidence showing that mutations can also exhibit …
stochastic force. However, there is ample evidence showing that mutations can also exhibit …
Variation of the adaptive substitution rate between species and within genomes
The importance of adaptive mutations in molecular evolution is extensively debated. Recent
developments in population genomics allow inferring rates of adaptive mutations by fitting a …
developments in population genomics allow inferring rates of adaptive mutations by fitting a …
Island songbirds as windows into evolution in small populations
Due to their limited ranges and inherent isolation, island species have long been recognized
as crucial systems for tackling a range of evolutionary questions, including in the early study …
as crucial systems for tackling a range of evolutionary questions, including in the early study …
An evolutionary perspective on genetic load in small, isolated populations as informed by whole genome resequencing and forward-time simulations
Small populations are vulnerable to increased genetic load and drift that can lead to
reductions in fitness and adaptive potential. By analyzing 66 individual whole genomes of …
reductions in fitness and adaptive potential. By analyzing 66 individual whole genomes of …
Strong evidence for the adaptive walk model of gene evolution in Drosophila and Arabidopsis
Understanding the dynamics of species adaptation to their environments has long been a
central focus of the study of evolution. Theories of adaptation propose that populations …
central focus of the study of evolution. Theories of adaptation propose that populations …
Adapting to climate with limited genetic diversity: Nucleotide, DNA methylation and microbiome variation among populations of the social spider Stegodyphus …
Understanding the role of genetic and nongenetic variants in modulating phenotypes is
central to our knowledge of adaptive responses to local conditions and environmental …
central to our knowledge of adaptive responses to local conditions and environmental …
Global adaptation complicates the interpretation of genome scans for local adaptation
Spatially varying selection promotes variance in allele frequencies, increasing genetic
differentiation between the demes of a metapopulation. For that reason, outliers in the …
differentiation between the demes of a metapopulation. For that reason, outliers in the …
The challenge and promise of estimating the de novo mutation rate from whole‐genome comparisons among closely related individuals
Germline mutations are the raw material for natural selection, driving species evolution and
the generation of earth's biodiversity. Without this driver of genetic diversity, life on earth …
the generation of earth's biodiversity. Without this driver of genetic diversity, life on earth …
Comparison of the full distribution of fitness effects of new amino acid mutations across great apes
Castellano et al. provide the first comparison of the full distribution of fitness effects
(including deleterious, neutral but also beneficial mutations) in the great apes. The authors …
(including deleterious, neutral but also beneficial mutations) in the great apes. The authors …