Vaginal microbiome: normalcy vs dysbiosis

VS Saraf, SA Sheikh, A Ahmad, PM Gillevet… - Archives of …, 2021 - Springer
It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …

Lactobacillus iners: friend or foe?

MI Petrova, G Reid, M Vaneechoutte, S Lebeer - Trends in microbiology, 2017 - cell.com
The vaginal microbial community is typically characterized by abundant lactobacilli.
Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal …

Emu: species-level microbial community profiling of full-length 16S rRNA Oxford Nanopore sequencing data

KD Curry, Q Wang, MG Nute, A Tyshaieva, E Reeves… - Nature …, 2022 - nature.com
Abstract 16S ribosomal RNA-based analysis is the established standard for elucidating the
composition of microbial communities. While short-read 16S rRNA analyses are largely …

Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health

MI Petrova, E Lievens, S Malik, N Imholz… - Frontiers in …, 2015 - frontiersin.org
The human body is colonized by a vast number of microorganisms collectively referred to as
the human microbiota. One of the main microbiota body sites is the female genital tract …

Vaginal microbiome and its relationship to behavior, sexual health, and sexually transmitted diseases

FMT Lewis, KT Bernstein, SO Aral - Obstetrics & Gynecology, 2017 - journals.lww.com
The vaginal microbiota has great significance in maintaining vaginal health and protecting
the host from disease. Recent advances in molecular techniques and informatics allow …

Reviewing the composition of vaginal microbiota: inclusion of nutrition and probiotic factors in the maintenance of eubiosis

A Barrientos-Durán, A Fuentes-López, A de Salazar… - Nutrients, 2020 - mdpi.com
The vaginal microbiota has importance in preserving vaginal health and defending the host
against disease. The advent of new molecular techniques and computer science has …

The interplay between reproductive tract microbiota and immunological system in human reproduction

S Al-Nasiry, E Ambrosino, M Schlaepfer… - Frontiers in …, 2020 - frontiersin.org
In the last decade, the microbiota, ie, combined populations of microorganisms living inside
and on the surface of the human body, has increasingly attracted attention of researchers in …

Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues

RA Ñahui Palomino, C Vanpouille, L Laghi… - Nature …, 2019 - nature.com
The vaginal microbiota, dominated by Lactobacillus spp., plays a key role in preventing HIV-
1 transmission. Here, we investigate whether the anti-HIV effect of lactobacilli is mediated by …

Lactobacillus-dominated cervicovaginal microbiota associated with reduced HIV/STI prevalence and genital HIV viral load in African women

H Borgdorff, E Tsivtsivadze, R Verhelst… - The ISME …, 2014 - academic.oup.com
Cervicovaginal microbiota not dominated by lactobacilli may facilitate transmission of HIV
and other sexually transmitted infections (STIs), as well as miscarriages, preterm births and …