Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma

A Barsouk, JS Aluru, P Rawla, K Saginala, A Barsouk - Medical Sciences, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving
the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together …

Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions

A Radaic, YL Kapila - Computational and structural biotechnology journal, 2021 - Elsevier
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …

Targeting biomolecular condensation and protein aggregation against cancer

JL Silva, D Foguel, VF Ferreira, TCRG Vieira… - Chemical …, 2023 - ACS Publications
Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

Aberrations of m6A regulators are associated with tumorigenesis and metastasis in head and neck squamous cell carcinoma

P Arumugam, R George, VP Jayaseelan - Archives of oral biology, 2021 - Elsevier
Abstract Objective N6-Methyladenosine (m6A) is the most common RNA modification in
eukaryotic mRNAs and growing evidence suggests that m6A modification and its regulators …

An updated review on head and neck cancer treatment with radiation therapy

G Anderson, M Ebadi, K Vo, J Novak, A Govindarajan… - Cancers, 2021 - mdpi.com
Simple Summary The mainstay of treatment for locoregionally advanced head and neck
squamous cell carcinoma (HNSCC) is either surgery followed by adjuvant radiation therapy …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Metastasis and MAPK pathways

M Kciuk, A Gielecińska, A Budzinska… - International journal of …, 2022 - mdpi.com
Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is
limited due to the metastasis of cells to distant locations of the body through the blood and …