Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly

R Young, M Haines, M Storch, PS Freemont - Metabolic Engineering, 2021 - Elsevier
Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …

[HTML][HTML] Space bioprocess engineering on the horizon

AJ Berliner, I Lipsky, D Ho, JM Hilzinger… - Communications …, 2022 - nature.com
Abstract Space bioprocess engineering (SBE) is an emerging multi-disciplinary field to
design, realize, and manage biologically-driven technologies specifically with the goal of …

[HTML][HTML] Engineered Pseudomonas putida simultaneously catabolizes five major components of corn stover lignocellulose: Glucose, xylose, arabinose, p-coumaric …

JR Elmore, GN Dexter, D Salvachúa, M O'Brien… - Metabolic …, 2020 - Elsevier
Valorization of all major lignocellulose components, including lignin, cellulose, and
hemicellulose is critical for an economically viable bioeconomy. In most biochemical …

[HTML][HTML] The synthetic biology open language (SBOL) version 3: simplified data exchange for bioengineering

JA McLaughlin, J Beal, G Mısırlı, R Grünberg… - … in Bioengineering and …, 2020 - frontiersin.org
The Synthetic Biology Open Language (SBOL) is a community-developed data standard that
allows knowledge about biological designs to be captured using a machine-tractable …

DNA-BOT: a low-cost, automated DNA assembly platform for synthetic biology

M Storch, MC Haines, GS Baldwin - Synthetic Biology, 2020 - academic.oup.com
Multi-part DNA assembly is the physical starting point for many projects in Synthetic and
Molecular Biology. The ability to explore a genetic design space by building extensive …

[HTML][HTML] Contemporary tools for regulating gene expression in bacteria

R Kent, N Dixon - Trends in Biotechnology, 2020 - cell.com
Insights from novel mechanistic paradigms in gene expression control have led to the
development of new gene expression systems for bioproduction, control, and sensing …

[HTML][HTML] Scaling up genetic circuit design for cellular computing: advances and prospects

Y Xiang, N Dalchau, B Wang - Natural computing, 2018 - Springer
Synthetic biology aims to engineer and redesign biological systems for useful real-world
applications in biomanufacturing, biosensing and biotherapy following a typical design-build …

Engineering synthetic regulatory circuits in plants

TK Kassaw, AJ Donayre-Torres, MS Antunes, KJ Morey… - Plant Science, 2018 - Elsevier
Plant synthetic biology is a rapidly emerging field that aims to engineer genetic circuits to
function in plants with the same reliability and precision as electronic circuits. These circuits …

Multiplexing cell‐cell communication

JT Sexton, JJ Tabor - Molecular systems biology, 2020 - embopress.org
The engineering of advanced multicellular behaviors, such as the programmed growth of
biofilms or tissues, requires cells to communicate multiple aspects of physiological …

Industrializing a Bacterial Strain for l-Serine Production through Translation Initiation Optimization

M Rennig, H Mundhada, GG Wordofa… - ACS synthetic …, 2019 - ACS Publications
Turning a proof-of-concept synthetic biology design into a robust, high performing cell
factory is a major time and money consuming task, which severely limits the growth of the …