The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle

J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

[HTML][HTML] The bacterial pangenome as a new tool for analysing pathogenic bacteria

L Rouli, V Merhej, PE Fournier, D Raoult - New microbes and new …, 2015 - Elsevier
The bacterial pangenome was introduced in 2005 and, in recent years, has been the subject
of many studies. Thanks to progress in next-generation sequencing methods, the …

Genome-scale metabolic reconstructions of multiple Escherichia coli strains highlight strain-specific adaptations to nutritional environments

JM Monk, P Charusanti, RK Aziz… - Proceedings of the …, 2013 - National Acad Sciences
Genome-scale models (GEMs) of metabolism were constructed for 55 fully sequenced
Escherichia coli and Shigella strains. The GEMs enable a systems approach to …

Horizontally transferred genetic elements and their role in pathogenesis of bacterial disease

C Gyles, P Boerlin - Veterinary pathology, 2014 - journals.sagepub.com
This article reviews the roles that laterally transferred genes (LTG) play in the virulence of
bacterial pathogens. The features of LTG that allow them to be recognized in bacterial …

Bacterial adaptation through loss of function

AK Hottes, PL Freddolino, A Khare, ZN Donnell… - PLoS …, 2013 - journals.plos.org
The metabolic capabilities and regulatory networks of bacteria have been optimized by
evolution in response to selective pressures present in each species' native ecological …

Emergence and evolution of virulence in human pathogenic fungi

S Siscar-Lewin, B Hube, S Brunke - Trends in microbiology, 2022 - cell.com
One billion people worldwide are affected by fungal pathogens, of which 1.6 million
succumb to fungal infections per year. This review discusses the emergence and evolution …

Genomic comparisons of Lactobacillus crispatus and Lactobacillus iners reveal potential ecological drivers of community composition in the vagina

MT France, H Mendes-Soares… - Applied and …, 2016 - Am Soc Microbiol
Lactobacillus crispatus and Lactobacillus iners are common inhabitants of the healthy
human vagina. These two species are closely related and are thought to perform similar …