Polymeric micelles in cancer therapy: State of the art
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
[HTML][HTML] Biodegradable polymeric nanoparticles for drug delivery to solid tumors
A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
The next generation of platinum drugs: targeted Pt (II) agents, nanoparticle delivery, and Pt (IV) prodrugs
TC Johnstone, K Suntharalingam, SJ Lippard - Chemical reviews, 2016 - ACS Publications
The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,
but new platinum agents have been very slow to enter the clinic. Recently, however, there …
but new platinum agents have been very slow to enter the clinic. Recently, however, there …
Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Renewable polyol-based biodegradable polyesters as greener plastics for industrial applications
The utilization of bio-based materials to develop sustainable products is an emerging area
of research. Renewable biomass-derived monomers have gained prominence in recent …
of research. Renewable biomass-derived monomers have gained prominence in recent …
Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress
Many different systems and strategies have been evaluated for drug targeting to tumors over
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles and …
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles and …
Overcoming the diffusion barrier of mucus and absorption barrier of epithelium by self-assembled nanoparticles for oral delivery of insulin
W Shan, X Zhu, M Liu, L Li, J Zhong, W Sun, Z Zhang… - ACS …, 2015 - ACS Publications
Nanoparticles (NPs) have demonstrated great potential for the oral delivery of protein drugs
that have very limited oral bioavailability. Orally administered NPs could be absorbed by the …
that have very limited oral bioavailability. Orally administered NPs could be absorbed by the …
Acid-degradable polymers for drug delivery: a decade of innovation
S Binauld, MH Stenzel - Chemical communications, 2013 - pubs.rsc.org
Polymers that start degrading under acidic conditions are increasingly investigated as a
pathway to trigger the release of drugs once the drug carrier reached the slightly acidic …
pathway to trigger the release of drugs once the drug carrier reached the slightly acidic …
Polymer–drug conjugates: Origins, progress to date and future directions
J Kopeček - Advanced drug delivery reviews, 2013 - Elsevier
This overview focuses on bioconjugates of water-soluble polymers with low molecular
weight drugs and proteins. After a short discussion of the origins of the field, the state-of-the …
weight drugs and proteins. After a short discussion of the origins of the field, the state-of-the …
Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …
Nowadays more and more attention is devoted to the application of those tools in the …