Polymeric micelles in cancer therapy: State of the art

B Ghosh, S Biswas - Journal of Controlled Release, 2021 - Elsevier
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

[HTML][HTML] Biodegradable polymeric nanoparticles for drug delivery to solid tumors

A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …

The next generation of platinum drugs: targeted Pt (II) agents, nanoparticle delivery, and Pt (IV) prodrugs

TC Johnstone, K Suntharalingam, SJ Lippard - Chemical reviews, 2016 - ACS Publications
The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,
but new platinum agents have been very slow to enter the clinic. Recently, however, there …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Renewable polyol-based biodegradable polyesters as greener plastics for industrial applications

KR Kunduru, R Hogerat, K Ghosal… - Chemical Engineering …, 2023 - Elsevier
The utilization of bio-based materials to develop sustainable products is an emerging area
of research. Renewable biomass-derived monomers have gained prominence in recent …

Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress

T Lammers, F Kiessling, WE Hennink… - Journal of controlled …, 2012 - Elsevier
Many different systems and strategies have been evaluated for drug targeting to tumors over
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles and …

Overcoming the diffusion barrier of mucus and absorption barrier of epithelium by self-assembled nanoparticles for oral delivery of insulin

W Shan, X Zhu, M Liu, L Li, J Zhong, W Sun, Z Zhang… - ACS …, 2015 - ACS Publications
Nanoparticles (NPs) have demonstrated great potential for the oral delivery of protein drugs
that have very limited oral bioavailability. Orally administered NPs could be absorbed by the …

Acid-degradable polymers for drug delivery: a decade of innovation

S Binauld, MH Stenzel - Chemical communications, 2013 - pubs.rsc.org
Polymers that start degrading under acidic conditions are increasingly investigated as a
pathway to trigger the release of drugs once the drug carrier reached the slightly acidic …

Polymer–drug conjugates: Origins, progress to date and future directions

J Kopeček - Advanced drug delivery reviews, 2013 - Elsevier
This overview focuses on bioconjugates of water-soluble polymers with low molecular
weight drugs and proteins. After a short discussion of the origins of the field, the state-of-the …

Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

M Barz, R Luxenhofer, R Zentel, MJ Vicent - Polymer Chemistry, 2011 - pubs.rsc.org
Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …