Metformin is a well-known anti-diabetic drug that has been repurposed for several emerging
applications, including as an anti-cancer agent. It boasts the distinct advantages of an …

Glioblastoma (GBM) is the most common and aggressive central nervous system tumor,
requiring multimodal management. Due to its malignant behavior and infiltrative growth …

Glioblastoma (GBM) constitutes the most common primary brain tumor in adults. The
challenges in GBM therapeutics have shed light on zebrafish used as a promising animal …

Glioblastoma (GB) is a highly malignant primary brain tumor with limited treatment options
and poor prognosis. Despite current treatment approaches, including surgical resection …

Gliomas are highly heterogeneous brain tumours that are resistant to therapies. The
molecular signatures of gliomas play a high-ranking role in tumour prognosis and treatment …

Simple Summary This research has been suggested after a gap was found in the previous
literature, and our hypothesis of the MMR vaccine being an oncolytic virus. The present …

Metformin, a first-line drug for type-2 diabetes, displays pleiotropic effects on inflammation,
aging, and cancer. Obesity triggers a low-grade chronic inflammation leading to insulin …

Background Meningiomas are mainly benign brain tumors, although about 20% of
histologically benign cases are clinically aggressive and recur after resection. We …

Based on the natural product terpestacin, seventeen derivatives (1–17) with various l-amino
acid side chains were designed and synthesized. Their anticancer activities against U87MG …

Introduction: Despite advances in comprehending cancer biology, malignant gliomas remain
incurable. The present work conducted a multi-omics analysis for investigating the …