Long non-coding RNA DLEU2 drives EMT and glycolysis in endometrial cancer through HK2 by competitively binding with miR-455 and by modulating the EZH2/miR …

P Dong, Y Xiong, Y Konno, K Ihira, N Kobayashi… - Journal of Experimental …, 2021 - Springer
Background Epithelial-to-mesenchymal transition (EMT) and aerobic glycolysis are
fundamental processes implicated in cancer metastasis. Although increasing evidence …

Biological functions and research progress of eIF4E

X Chen, Y An, M Tan, D Xie, L Liu, B Xu - Frontiers in Oncology, 2023 - frontiersin.org
The eukaryotic translation initiation factor eIF4E can specifically bind to the cap structure of
an mRNA 5'end, mainly regulating translation initiation and preferentially enhancing the …

Anesthetics may modulate cancer surgical outcome: a possible role of miRNAs regulation

M Ishikawa, M Iwasaki, A Sakamoto, D Ma - BMC anesthesiology, 2021 - Springer
Background microRNAs (miRNAs) are single-stranded and noncoding RNA molecules that
control post-transcriptional gene regulation. miRNAs can be tumor suppressors or …

MicroRNA-455-3p as a potential biomarker for Alzheimer's disease: an update

S Kumar, PH Reddy - Frontiers in aging neuroscience, 2018 - frontiersin.org
A non-invasive and early-detectable peripheral biomarker is urgently needed for Alzheimer's
disease (AD). The present study is a step forward to verify the biomarker properties of …

Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

A Liu, J Zhu, G Wu, L Cao, Z Tan, S Zhang, L Jiang… - Molecular cancer, 2017 - Springer
Background The plasticity of cancer stem cells (CSCs)/tumor-initiating cells (T-ICs) suggests
that multiple CSC/T-IC subpopulations exist within a tumor and that multiple oncogenic …

Identification of novel genes associated with a poor prognosis in pancreatic ductal adenocarcinoma via a bioinformatics analysis

J Zhou, X Hui, Y Mao, L Fan - Bioscience Reports, 2019 - portlandpress.com
Pancreatic ductal adenocarcinoma (PDAC) is a class of the commonest malignant
carcinomas. The present study aimed to elucidate the potential biomarker and prognostic …

Silencing of DLEU2 suppresses pancreatic cancer cell proliferation and invasion by upregulating microRNA‐455

B Xu, X Gong, L Zi, G Li, S Dong, X Chen… - Cancer science, 2019 - Wiley Online Library
Long noncoding RNA (lnc RNA) DLEU 2 has been shown to be dysregulated in several type
of tumor. However, the potential biological roles and molecular mechanisms of DLEU 2 in …

miR-455-3p serves as prognostic factor and regulates the proliferation and migration of non-small cell lung cancer through targeting HOXB5

X Gao, H Zhao, C Diao, X Wang, Y Xie, Y Liu… - Biochemical and …, 2018 - Elsevier
MicroRNAs (miRs) have been reported to play significantly roles in the initiation and
progression of human cancers. miR-455-3p has been recently found could function as tumor …

Detection of increased serum miR-122-5p and miR-455-3p levels before the clinical diagnosis of liver cancer in people with type 2 diabetes

HM Lee, WKK Wong, B Fan, ES Lau, Y Hou, CK O… - Scientific Reports, 2021 - nature.com
People with type 2 diabetes (T2D) have increased cancer risk. Liver cancer (LC) has a high
prevalence in East Asia and is one of the leading causes of cancer death globally …

CircLRP6 regulation of ZEB1 via miR-455 is involved in the epithelial-mesenchymal transition during arsenite-induced malignant transformation of human …

J Xue, C Chen, F Luo, X Pan, H Xu, P Yang… - Toxicological …, 2018 - academic.oup.com
Circular RNAs (circRNAs), a class of noncoding RNAs generated from pre-mRNAs,
participate in the regulation of tumorigenesis. The mechanism for regulation, however, is …