Physiological transformation with remodeling of the uteroplacental spiral arteries is key to a
successful placentation and normal placental function. It is an intricate process that involves …

All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …

During pregnancy the maternal–fetal interface plays vital roles in fetal development. Its
disruption is frequently found in pregnancy complications. Recent studies show increased …

Hormonal changes during pregnancy instigate numerous physiological changes aimed at
the growth and delivery of a healthy baby. A careful balance between immunological …

The human endometrium is essential in providing the site for implantation and maintaining
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …

Historically, invasion of placental trophoblasts was thought to be extremely specific, only
invading into the connective tissues of the maternal uterus and finally reaching and …

Changes in maternal nutrient availability due to diet or disease significantly increase the risk
of neural tube defects (NTDs). Because the incidence of metabolic disease continues to rise …

Human pregnancy depends on the proper development of the embryo prior to implantation
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …

Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …

Rationale: Recurrent pregnancy loss (RPL) is a distressing disorder that seriously affects the
physical and psychological health of women. RPL is also a sentinel risk marker for future …