Current state and future directions of genetics and genomics of endophytic fungi for bioprospecting efforts

R Sagita, WJ Quax, K Haslinger - Frontiers in Bioengineering and …, 2021 - frontiersin.org
The bioprospecting of secondary metabolites from endophytic fungi received great attention
in the 1990s and 2000s, when the controversy around taxol production from Taxus spp …

Rethinking of the Roles of Endophyte Symbiosis and Mycotoxin in Oxytropis Plants

H Guan, X Liu, LAJ Mur, Y Fu, Y Wei, J Wang, W He - Journal of Fungi, 2021 - mdpi.com
Plants in the Oxytropis genus can live with the endophytic fungi Alternaria sect. Undifilum.
Swainsonine, the mycotoxin produced by the endophyte render the host plant toxic and this …

Assembly of high‐quality genomes of the locoweed Oxytropis ochrocephala and its endophyte Alternaria oxytropis provides new evidence for their symbiotic …

L Zhang, R Wu, LAJ Mur, C Guo, X Zhao… - Molecular Ecology …, 2023 - Wiley Online Library
Locoweeds are perennial forbs poisonous to livestock and cause extreme losses to animal
husbandry. Locoweed toxicity is attributed to the symbiotic endophytes in Alternaria sect …

Transcriptomic Screening of Alternaria oxytropis Isolated from Locoweed Plants for Genes Involved in Mycotoxin Swaisonine Production

S Yuan, Q Zhao, K Yu, Y Gao, Z Ma, H Li, Y Yu - Journal of Fungi, 2024 - mdpi.com
Locoweed is a collective name for a variety of plants, such as Oxytropis and Astragalus L.
When these plants are infected by some fungi or endophytes, they will produce an alkaloid …

Localization of the Swainsonine-Producing Chaetothyriales Symbiont in the Seed and Shoot Apical Meristem in Its Host Ipomoea carnea

M Neyaz, DR Gardner, R Creamer, D Cook - Microorganisms, 2022 - mdpi.com
Several species of fungi from the orders Chaetothyriales and Pleosporales have been
reported to produce swainsonine and be associated as symbionts with plants of the …

Phylogenetic comparison of swainsonine biosynthetic gene clusters among fungi

M Neyaz, S Das, D Cook, R Creamer - Journal of Fungi, 2022 - mdpi.com
Swainsonine is a cytotoxic alkaloid produced by fungi. Genome sequence analyses
revealed that these fungi share an orthologous gene cluster, SWN, necessary for …

swnk plays an important role in the biosynthesis of swainsonine in Metarhizium anisopliae

E Huang, Y Zhang, L Sun, Y Zhu, S Tang, C Mo… - Biotechnology …, 2023 - Springer
Objective Swainsonine (SW) is the principal toxic ingredient of locoweeds, and is produced
by multiple fungi. A key enzyme in the SW synthesis pathway is a hybrid swnk/nrps. To …

Endophytic fungi and their bioactive secondary metabolites in medicinal leguminosae plants: Nearly untapped medical resources

ZY Zhou, X Liu, JL Cui, JH Wang… - FEMS Microbiology …, 2022 - academic.oup.com
There are many species of Chinese traditional leguminosae family plants that are well
known for their medicinal applications, such as Astragalus membranaceus, Catsia tora …

Identification and distribution of a fungal endosymbiotic Alternaria species (Alternaria section Undifilum sp.) in Astragalus garbancillo tissues

ME Pistán, D Cook, SA Gutiérrez, L Schnittger… - Mycologia, 2024 - Taylor & Francis
Plants belonging to the genera Astragalus, Oxytropis, Ipomoea, Sida, and Swainsona often
contain the toxin swainsonine (SW) produced by an associated fungal symbiont …

[HTML][HTML] 甲基磺酸乙酯诱变的棘豆链格孢菌菌株苦马豆素合成基因簇相关基因表达模式分析

余永涛, 毛彦妮, 赵清梅, 李金荣, 白晓南, 薛佳祺… - 畜牧兽医学报, 2022 - html.rhhz.net
旨在对棘豆链格孢菌SWN 基因簇各基因表达模式与苦马豆素合成的相关性进行分析.
本研究应用甲基磺酸乙酯(EMS) 对棘豆链格孢菌UA003 诱变处理, 筛选苦马豆素产率显著变化 …