[HTML][HTML] Impact of primary tumour location on colorectal liver metastases: A systematic review

G Bingham, A Shetye, R Suresh… - World Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Colorectal cancer (CRC) is the third most common cause of cancer-related
death worldwide. Despite significant advances in screening, surgical management and …

Gene mutation and surgical technique: Suggestion or more?

Y Kawaguchi, HA Lillemoe, JN Vauthey - Surgical oncology, 2020 - Elsevier
Advancements in chemotherapy and molecular targeted therapy have improved long-term
outcomes for patients with resectable colorectal liver metastases (CLM). RAS mutation …

[HTML][HTML] Response to preoperative chemotherapy: impact of change in total burden score and mutational tumor status on prognosis of patients undergoing resection …

A Ruzzenente, F Bagante, F Ratti, EW Beal… - HPB, 2019 - Elsevier
Background Progression of colorectal liver metastasis (CRLM) on preoperative
chemotherapy has been associated with a worse prognosis compared with patients who …

Imaging predictors of BRAF mutation in colorectal cancer

K Eurboonyanun, RM Lahoud, H Kordbacheh… - Abdominal …, 2020 - Springer
Background Colorectal cancer (CRC) is one of the leading causes of cancer deaths and is
associated with various genetic mutations. BRAF mutations, found in approximately 10% of …

Nuclear Localization of BRAFV600E Is Associated with HMOX-1 Upregulation and Aggressive Behavior of Melanoma Cells

M Zerfaoui, E Toraih, E Ruiz, Y Errami, AS Attia… - Cancers, 2022 - mdpi.com
Simple Summary Despite some successes of selective anti-BRAFV600E inhibitors,
resistance remains a major challenge. The aim of our study is to determine the role of …

Molecular determinants and other factors to guide selection of patients for hepatic resection of metastatic colorectal cancer

TM Diehl, DE Abbott - Current treatment options in oncology, 2021 - Springer
Opinion statement Treatment for metastatic colorectal cancer (CRC) has changed
significantly over the last few decades as cytotoxic and targeted chemotherapies have …

Reevaluating the prognostic role of BRAF mutation in colorectal cancer liver metastases

A Pikouli, D Papaconstantinou, J Wang… - The American Journal of …, 2022 - Elsevier
Introduction Mutations in the BRAF proto-oncogene have been shown to predict poor patient
survival following curative-intent liver surgery for metastatic colorectal cancer. The aim of the …

[PDF][PDF] Deep learning-derived spatial organization features on histology images predicts prognosis in colorectal liver metastasis patients after hepatectomy

L Qi, J Liang, Z Li, S Xi, Y Lai, F Gao, X Zhang, D Wang… - Iscience, 2023 - cell.com
Histopathological images of colorectal liver metastases (CRLM) contain rich morphometric
information that may predict patients' outcomes. However, to our knowledge, no study has …

[HTML][HTML] Simultaneous colorectal and parenchymal-sparing liver resection for advanced colorectal carcinoma with synchronous liver metastases: Between …

E De Raffele, M Mirarchi, D Cuicchi… - World Journal of …, 2020 - ncbi.nlm.nih.gov
The optimal timing of surgery in case of synchronous presentation of colorectal cancer and
liver metastases is still under debate. Staged approach, with initial colorectal resection …

Optimizing Outcomes in Minimally Invasive Resections of Colorectal Liver Metastases

PT Mavani, MM Shah - JAMA Network Open, 2024 - jamanetwork.com
The Minimally Invasive, Indocyanine-Guided Metastasectomy in Patients With Colorectal
Liver Metastases (MIMIC) trial, a single-arm prospective multicenter cohort study conducted …