Studies have demonstrated that structural variants (SV) play a substantial role in the
evolution of species and have an impact on Mendelian traits in the genome. However, unlike …

Horns are the most obvious common feature of Bovidae. The naturally occurring absence of
horns in these species, also known as polledness, is of surprisingly heterogeneous nature …

Background There is a long-term interest in investigating the genetic basis of the
horned/polled phenotype in domestic goats. Here, we report a genome-wide association …

Background Breeding polled goats is a welfare-friendly approach for horn removal in
comparison to invasive methods. To gain a comprehensive understanding of the genetic …

Harmful alleles can be under balancing selection due to an interplay of artificial selection for
the variant in heterozygotes and purifying selection against the variant in homozygotes …

Background Differences of sex development (DSD) are congenital conditions in which
chromosomal, gonadal, or phenotypic sex is atypical. In more than 50% of human DSD …

Simple Summary Freemartinism is the most common type of disorder of sex development
(DSD) in heifers; it is caused by the formation of placental anastomoses between …

Pigs serve as a robust animal model for the study of human diseases, notably in the context
of disorders of sex development (DSD). This study aims to investigate the phenotypic …

Background: Polled intersex syndrome (PIS) leads to reproductive disorders in goats and
exerts a heavy influence on goat breeding. Since 2001, the core variant of an 11.7 kb …

Disorders of sex development (DSDs) are congenital malformations defined as
discrepancies between sex chromosomes and phenotypical sex. Testicular or ovotesticular …