States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key
clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host …

In evaluating the pathogenesis of periodontal diseases, the diagnostic potential of gingival
crevicular fluid has been extensively explored during the last twenty years, from initially just …

Recent studies have highlighted the importance of the human microbiome in health and
disease. However, for the most part the mechanisms by which the microbiome mediates …

Recent advancements in the periodontal research field are consistent with a new model of
pathogenesis according to which periodontitis is initiated by a synergistic and dysbiotic …

The hypoxic microenvironment, continuous oxygen consumption, and poor excitation light
penetration depth during antimicrobial photodynamic therapy (aPDT) tremendously hinder …

Periodontitis is a chronic inflammatory condition of the periodontium involving interactions
between bacterial products, numerous cell populations and inflammatory mediators. It is …

Caries and periodontitis are the two most common human dental diseases and are caused
by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to …