Worldwide, familial and epidemiological studies have generated considerable evidence of
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …

Genome-wide association studies (GWAS) provide an important avenue for undertaking an
agnostic evaluation of the association between common genetic variants and risk of …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To
identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

We created a deeply extracted and annotated database of genome-wide association studies
(GWAS) results. GRASP v1. 0 contains> 6.2 million SNP-phenotype association from among …

Prostate cancer (PrCa) is the most frequently diagnosed cancer in males in developed
countries. To identify common PrCa susceptibility alleles, we previously conducted a …

We report a prostate cancer genome-wide association follow-on study. We discovered four
variants associated with susceptibility to prostate cancer in several European populations …

The Melbourne Collaborative Cohort Study (MCCS), also known as Health 2020, was
planned in the late 1980s and established in the early 1990s as an omnibus cohort to …

Approaches to reduce the global burden of cancer include two major strategies: screening
and early detection and active preventive intervention. The latter is the topic of this …

GWAS of prostate cancer have been remarkably successful in revealing common genetic
variants and novel biological pathways that are linked with its etiology. A more complete …

Background Epidemiological studies suggest a potential role for obesity and determinants of
adult stature in prostate cancer risk and mortality, but the relationships described in the …