Neuroinflammation, a protective response of the central nervous system (CNS), is
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …

The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …

Neurodegenerative diseases are chronic, progressive disorders that occur in the central
nervous system (CNS). They are characterized by the loss of neuronal structure and function …

Interactome maps are valuable resources to elucidate protein function and disease
mechanisms. Here, we report on an interactome map that focuses on neurodegenerative …

Bacopa monnieri (Brahmi) is a well-known perennial, creeping herb of the Indian Ayurveda
system; it contains numerous bioactive phytoconstituents implicated in the therapeutic …

The potential to treat neurodegenerative diseases (NDs) of the major bioactive compound of
green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now …

In the pathophysiology of neurodegenerative disorders, the role of misfolded protein
deposition leading to neurodegeneration has been primarily discussed. In the last decade …

Abstract Cyclin-dependent kinase 5 (CDK5) is the serine/threonine-directed kinase mainly
found in the brain and plays a significant role in developing the central nervous system …

Microtubule affinity regulating kinase 4 (MARK4) is known to hyperphosphorylate tau
protein, which subsequently causes Alzheimer's disease (AD). MARK4 is a well-validated …

Palmatine is a naturally occurring isoquinoline alkaloid that has been reported to display
neuroprotective effects against amyloid‐β‐(Aβ‐) induced neurotoxicity. However, the …