Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer

L Buscail, B Bournet, P Cordelier - Nature reviews Gastroenterology & …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is predicted to be the second most common
cause of death within the next 10 years. The prognosis for this disease is poor despite …

Pancreatic cancer

T Kamisawa, LD Wood, T Itoi, K Takaori - The Lancet, 2016 - thelancet.com
Pancreatic cancer is a highly lethal disease, for which mortality closely parallels incidence.
Most patients with pancreatic cancer remain asymptomatic until the disease reaches an …

Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) …

JM Dumonceau, PH Deprez, C Jenssen… - …, 2017 - thieme-connect.com
For pancreatic solid lesions, ESGE recommends performing endoscopic ultrasound (EUS)-
guided sampling as first-line procedure when a pathological diagnosis is required …

Detection of K‐ras gene mutation by liquid biopsy in patients with pancreatic cancer

H Kinugasa, K Nouso, K Miyahara, Y Morimoto… - Cancer, 2015 - Wiley Online Library
BACKGROUND Cell‐free circulating tumor DNA (ctDNA) in serum has been considered to
be a useful candidate for noninvasive cancer diagnosis. The current study was designed to …

[HTML][HTML] Targeting KRAS for diagnosis, prognosis, and treatment of pancreatic cancer: Hopes and realities

B Bournet, C Buscail, F Muscari, P Cordelier… - European journal of …, 2016 - Elsevier
Mutation of the KRAS oncogene in pancreatic cancer is responsible for permanent activation
of the P21 RAS protein and the cascade of signalling pathways. Consequently, multiple …

[HTML][HTML] Advances in pancreatic cancer biomarkers

S Hasan, R Jacob, U Manne, R Paluri - Oncology reviews, 2019 - ncbi.nlm.nih.gov
Biomarkers play an essential role in the management of patients with invasive cancers.
Pancreatic ductal adenocarcinoma (PDC) associated with poor prognosis due to advanced …

Analysis of ctDNA to predict prognosis and monitor treatment responses in metastatic pancreatic cancer patients

HE Cheng, C Liu, J Jiang, G Luo, Y Lu… - … journal of cancer, 2017 - Wiley Online Library
Cell‐free circulating tumor DNA (ctDNA) in plasma has been used as a potential
noninvasive biomarker for various tumors. Our study was performed to evaluate the clinical …

EFSUMB guidelines on interventional ultrasound (INVUS), Part IV–EUS-guided interventions: General aspects and EUS-guided sampling (long version)

C Jenssen, M Hocke, P Fusaroli… - Ultraschall in der …, 2016 - thieme-connect.com
The fourth part of the European Federation of Societies for Ultrasound in Medicine and
Biology (EFSUMB) Guidelines on Interventional Ultrasound describes general aspects of …

KRAS G12D Mutation Subtype in Pancreatic Ductal Adenocarcinoma: Does It Influence Prognosis or Stage of Disease at Presentation?

H Shen, J Lundy, AH Strickland, M Harris, M Swan… - Cells, 2022 - mdpi.com
Background: KRAS G12D mutation subtype is present in over 40% of pancreatic ductal
adenocarcinoma (PDAC), one of the leading global causes of cancer death. This …

A quarter century of EUS-FNA: Progress, milestones, and future directions

IM Cazacu, AAL Chavez, A Saftoiu… - Endoscopic …, 2018 - journals.lww.com
Tissue acquisition using EUS has considerably evolved since the first EUS-FNA was
reported 25 years ago. Its introduction was an important breakthrough in the endoscopic …