Psoriasis is defined as chronic, immune‐mediated disease. Regardless of the development
of new therapeutic approaches, the precise etiology of psoriasis remains unknown and …

Hepatocellular Carcinoma (HCC) continues to pose a substantial global health challenge
due to its high incidence and limited therapeutic options. In recent years, the Janus Kinase …

Simple Summary Lung cancer is currently the second leading cause of cancer death
worldwide. Cytokines are small proteins that carry messages between cells and are known …

The importance of IL‐23 and its specific receptor, IL‐23R, in the pathogenesis of several
chronic inflammatory diseases has been established, but the underlying pathological …

Patients with immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis
and inflammatory bowel disease, are at increased risk of infection. International guidelines …

Abstract Interleukin (IL)-12 family cytokines including IL-12, IL-23, IL-27, IL-35 and IL-39 are
heterodimeric cytokines composed of two subunits, an α-chain (entitled p35, p19 and p28) …

Rheumatic diseases are complex autoimmune diseases which include among others
rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), and psoriatic arthritis (PsA) …

Senescent T cells are proliferative disabled lymphocytes that lack antigen-specific
responses. The development of T-cell senescence in autoimmune diseases contributes to …

Sarcoidosis is a chronic inflammatory disorder, which is characterized by noncaseating
granulomas impairing organ function. It is a multisystem condition that can affect any organ …

Pregnant women are highly susceptible to infection by the bacterial pathogen Listeria
monocytogenes, leading to miscarriage, premature birth, and neonatal infection. L …