Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
The Pharmacological Potential of Adenosine A2A Receptor Antagonists for Treating Parkinson's Disease
A Mori, JF Chen, S Uchida, C Durlach, SM King… - Molecules, 2022 - mdpi.com
The adenosine A2A receptor subtype is recognized as a non-dopaminergic
pharmacological target for the treatment of neurodegenerative disorders, notably …
pharmacological target for the treatment of neurodegenerative disorders, notably …
Telephone-based cognitive behavioral therapy for depression in Parkinson disease: a randomized controlled trial
Objective To determine whether, for patients with depression and Parkinson disease (PD),
telephone-based cognitive-behavioral treatment (T-CBT) alleviates depressive symptoms …
telephone-based cognitive-behavioral treatment (T-CBT) alleviates depressive symptoms …
Parkinson and depression: review and outlook
G Laux - Journal of neural transmission, 2022 - Springer
Abstract Depression in Parkinson's Disorder (DPD) has been estimated to appear in up to
40% of people with PD and negatively impacts quality of life, motor and cognitive deficits …
40% of people with PD and negatively impacts quality of life, motor and cognitive deficits …
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing
NJ Mekkes, M Groot, E Hoekstra, A de Boer… - Nature medicine, 2024 - nature.com
Neurodegenerative disorders exhibit considerable clinical heterogeneity and are frequently
misdiagnosed. This heterogeneity is often neglected and difficult to study. Therefore …
misdiagnosed. This heterogeneity is often neglected and difficult to study. Therefore …
Drug-induced gambling disorder: epidemiology, neurobiology, and management
M Wolfschlag, A Håkansson - Pharmaceutical medicine, 2023 - Springer
Problematic gambling has been suggested to be a possible consequence of dopaminergic
medications used mainly in neurological conditions, ie pramipexole and ropinirole, and …
medications used mainly in neurological conditions, ie pramipexole and ropinirole, and …
Depression in major neurodegenerative diseases and strokes: a critical review of similarities and differences among neurological disorders
J Pagonabarraga, C Álamo, M Castellanos, S Díaz… - Brain Sciences, 2023 - mdpi.com
Depression and anxiety are highly prevalent in most neurological disorders and can have a
major impact on the patient's disability and quality of life. However, mostly due to the …
major impact on the patient's disability and quality of life. However, mostly due to the …
Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease
D Weintraub, C Caspell‐Garcia… - Annals of clinical …, 2020 - Wiley Online Library
Objective To determine the evolution of numerous neuropsychiatric symptoms and cognitive
abilities in Parkinson disease from disease onset. Methods Prospectively collected …
abilities in Parkinson disease from disease onset. Methods Prospectively collected …
Depression and anxiety among patients with Parkinson's disease: frequency, risk factors, and impact on quality of life
Background Depression and anxiety are non-motor symptoms of Parkinson's disease (PD)
that are often overlooked and underrated. This study aimed to highlight the frequency and …
that are often overlooked and underrated. This study aimed to highlight the frequency and …
Anxiety, depression, and worries in advanced Parkinson disease during COVID-19 pandemic
E Montanaro, CA Artusi, C Rosano, C Boschetto… - Neurological …, 2022 - Springer
Background The psychological impact of the COVID-19 outbreak and lockdown on frail
populations with advanced Parkinson disease (APD) and their caregivers may present with …
populations with advanced Parkinson disease (APD) and their caregivers may present with …