Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …

There are many pathways of endocytosis at the cell surface that apparently operate at the
same time. With the advent of new molecular genetic and imaging tools, an understanding of …

Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …

Targeting of drugs and their carrier systems by using receptor-mediated endocytotic
pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …

There are numerous ways that endocytic cargo molecules may be internalized from the
surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of …

Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

Several cell surface molecules including signalling receptors are internalized by clathrin-
independent endocytosis. How this process is initiated, how cargo proteins are sorted and …

Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic
itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new …

How endocytic pits are built in clathrin-and caveolin-independent endocytosis still remains
poorly understood. Recent insight suggests that different forms of clathrin-independent …

Plasma membrane tension regulates many key cellular processes. It is modulated by, and
can modulate, membrane trafficking. However, the cellular pathway (s) involved in this …