Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19
S Wolfisberg, C Gregoriano… - Critical reviews in clinical …, 2022 - Taylor & Francis
Procalcitonin (PCT) is useful for differentiating between viral and bacterial infections and for
reducing the unnecessary use of antibiotics. As the rise of antimicrobial resistance reaches …
reducing the unnecessary use of antibiotics. As the rise of antimicrobial resistance reaches …
Host diagnostic biomarkers of infection in the ICU: where are we and where are we going?
AJ Heffernan, KJ Denny - Current infectious disease reports, 2021 - Springer
Abstract Purpose of Review Early identification of infection in the critically ill patient and
initiation of appropriate treatment is key to reducing morbidity and mortality. On the other …
initiation of appropriate treatment is key to reducing morbidity and mortality. On the other …
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa …
J Chastre, B François, M Bourgeois, A Komnos… - Critical Care, 2022 - Springer
Background Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in
hospitalised patients is associated with high mortality. The effectiveness of the bivalent …
hospitalised patients is associated with high mortality. The effectiveness of the bivalent …
Monocyte distribution width (MDW) as a screening tool for sepsis in the Emergency Department
Objectives The diagnosis of sepsis in the Emergency Department (ED) is challenging and a
reliable biomarker is needed. The current study aimed to evaluate the diagnostic accuracy of …
reliable biomarker is needed. The current study aimed to evaluate the diagnostic accuracy of …
The pathophysiology of sepsis—2021 update: Part 2, organ dysfunction and assessment
J Jacobi - American Journal of Health-System Pharmacy, 2022 - academic.oup.com
Purpose This is the second article in a 2-part series discussing the pathophysiology of
sepsis. Part 1 of the series reviewed the immunologic response and overlapping pathways …
sepsis. Part 1 of the series reviewed the immunologic response and overlapping pathways …
The ability of Procalcitonin, lactate, white blood cell count and neutrophil-lymphocyte count ratio to predict blood stream infection. Analysis of a large database
PE Marik, E Stephenson - Journal of Critical Care, 2020 - Elsevier
Background The global burden of death due to sepsis is considerable. Early diagnosis is
essential to improve the outcome of this deadly syndrome. Yet, the diagnosis of sepsis is …
essential to improve the outcome of this deadly syndrome. Yet, the diagnosis of sepsis is …
Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells
Z Wei, J Xu, C Zhao, M Zhang, N Xu, L Kang… - Frontiers in …, 2023 - frontiersin.org
Introduction CAR-T cell therapy is a novel approach in the treatment of hematological
tumors. However, it is associated with life-threatening side effects, such as the severe …
tumors. However, it is associated with life-threatening side effects, such as the severe …
Comparison and analysis of polymer-functionalized carbon nanotubes for enhancement of the quantitative detection of procalcitonin levels in human plasma
Procalcitonin (PCT) is one of the core biomarkers for the body's systemic inflammatory
response that is expressed uniformly in several organ tissues. PCT concentration levels rise …
response that is expressed uniformly in several organ tissues. PCT concentration levels rise …
Platelet indices and their kinetics predict mortality in patients of sepsis
S Mangalesh, S Dudani, A Malik - Indian Journal of Hematology and Blood …, 2021 - Springer
Platelet indices are inexpensive, easily accessible parameters and potentially useful
prognostic indicators in sepsis. In this study we explore the differences in platelet indices …
prognostic indicators in sepsis. In this study we explore the differences in platelet indices …
Procalcitonin as a biomarker for predicting bacterial infection in chimeric antigen receptor T‐cell therapy recipients
MZ Powell, KC Mara, R Bansal, MA Hathcock… - Cancer …, 2023 - Wiley Online Library
Background It is unknown whether serum procalcitonin (PCT) concentration monitoring can
differentiate between bacterial infection or cytokine release syndrome (CRS) when chimeric …
differentiate between bacterial infection or cytokine release syndrome (CRS) when chimeric …