The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …

Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central
nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis …

The gut microbiota regulates T cell functions throughout the body. We hypothesized that
intestinal bacteria impact the pathogenesis of multiple sclerosis (MS), an autoimmune …

The gut microbiome plays an important role in immune function and has been implicated in
several autoimmune disorders. Here we use 16S rRNA sequencing to investigate the gut …

Almost half the cells and 1% of the unique genes found in our bodies are human, the rest
are from microbes, predominantly bacteria, archaea, fungi, and viruses. These …

B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that
preferentially affects the spinal cord and optic nerve. Most patients with NMOSD experience …

Purpose Gut microbiota regulate intestinal function and health. However, mounting evidence
indicates that they can also influence the immune and nervous systems and vice versa. This …

In recent years evidence has emerged that neurodegenerative diseases (NDs) are strongly
associated with the microbiome composition in the gut. Parkinson's disease (PD) is the most …

Mammals live in a co-evolutionary association with the plethora of microorganisms that
reside at a variety of tissue microenvironments. The microbiome represents the collective …