The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …

Dense, complex microbial communities, collectively termed the microbiota, occupy a diverse
array of niches along the length of the mammalian intestinal tract. During health and in the …

Background Clostridium difficile is the leading cause of antibiotic-associated diarrhoea, both
in healthcare facilities and in the community. The recurrence rate of C. difficile infection (CDI) …

The human gastrointestinal tract is home to an extremely numerous and diverse collection of
microbes, collectively termed the “intestinal microbiota”. This microbiota is considered to …

Antimicrobial resistance (AMR) is a major public health issue, causing 5 million deaths per
year. Without any action plan, AMR will be in a near future the leading cause of death ahead …

The current picture of Clostridium difficile infection (CDI) is alarming with a mortality rate
ranging between 3% and 15% and a CDI recurrence rate ranging from 12% to 40%. Despite …

Clostridium difficile is the leading infectious cause of antibiotic‐associated diarrhea and
colitis. C. difficile infection (CDI) places a heavy burden on the healthcare system, with …

Anaerobic bacteria are the predominant indigenous flora of humans and, as a result, play an
important role in infections, some of which are serious with a high mortality rate. These …

Clostridium difficile infection (CDI) presents a rapidly evolving challenge in the battle against
hospital-acquired infections. Recent advances in CDI diagnosis and management include …

Antimicrobial agents are currently the mainstay of treatment for bacterial infections
worldwide. However, due to the increased use of antimicrobials in both human and animal …